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Acute Myeloid Leukemia clinical trials in California

79 studies for Acute Myeloid Leukemia are looking for participants at sites in California.

Cities in California

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

  • City of Hope Center (City of Hope National Medical Center, City of Hope Medical Center), Duarte
RecruitingPhase 1
Ages 65 and older · All sexes · Updated Nov 13, 2026 · NCT06552416

Olutasidenib With Azacitidine Followed by Olutasidenib Maintenance for the Treatment of IDH1-mutated Acute Myeloid Leukemia in Patients With Prior Treatment With Venetoclax Plus a Hypomethylating Agent

  • UCLA Jonsson Comprehensive Cancer Center, Los Angeles
  • UCI Health Chao Family Comprehensive Cancer Center, Orange
  • University of California Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07304011

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

  • Kaiser Permanente Dublin, Dublin
  • Kaiser Permanente-Fremont, Fremont
  • Kaiser Permanente Fresno Orchard Plaza, Fresno
  • and 17 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06317649

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

  • University of California, Fresno, Clovis
  • University of California, San Diego, La Jolla
  • Cedars-Sinai Medical Center, Los Angeles
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07007312

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

  • Cedars-Sinai Medical Center, Los Angeles
  • Kaiser Permanente-Oakland, Oakland
  • Kaiser Permanente-Roseville, Roseville
  • and 3 more
RecruitingPhase 2
Ages 18 to 59 · All sexes · Updated Nov 9, 2026 · NCT05554406

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT05672147

HPC Offered for PRESERVE Expansion

  • City of Hope, Duarte
RecruitingObservational study
Ages 12 to 80 · All sexes · Updated Nov 6, 2026 · NCT07145411

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

  • US-Los Angeles CA-UCLA, Los Angeles
  • US-San Francisco CA-UCSF, San Francisco
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07223814

A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML

  • City of Hope Center Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07751991

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
  • PCR Oncology, Arroyo Grande
  • AIS Cancer Center at San Joaquin Community Hospital, Bakersfield
  • and 22 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

  • City of Hope, Duarte
  • City of Hope Orange County Lennar Foundation Cancer Center, Irvine
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06852222

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

  • Kaiser Permanente Dublin, Dublin
  • Kaiser Permanente-Fremont, Fremont
  • Kaiser Permanente Fresno Orchard Plaza, Fresno
  • and 19 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT05564390

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

  • City of Hope Comprehensive Cancer Center - Duarte, Duarte
  • University of California Los Angeles (UCLA) - David Geffen School of Medicine, Los Angeles
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 30, 2026 · NCT05429632

Study of REM-422 in Patients With AML or Higher Risk MDS

  • City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06297941

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

  • City of Hope, Duarte
  • UCLA, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT05143996

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

  • Cedars-Sinai Medical Center, Los Angeles
  • Kaiser Permanente-Oakland, Oakland
  • Kaiser Permanente-Roseville, Roseville
  • and 2 more
RecruitingPhase 2
Ages 18 to 59 · All sexes · Updated Oct 28, 2026 · NCT05554393

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

  • UCSF Medical Center-Parnassus, San Francisco
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06672146

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

  • City of Hope Medical Center, Duarte
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Oct 23, 2026 · NCT06059391

A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

  • City of Hope Comprehensive Cancer Center, Duarte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT06969430

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

  • City of Hope Medical Center, Duarte
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Oct 23, 2026 · NCT07020533

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

  • Rady Children's Hospital, San Diego
RecruitingPhase 1
Ages 1 to 30 · All sexes · Updated Oct 22, 2026 · NCT06177067

CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

  • University of California, Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 1
Ages 18 to 85 · All sexes · Updated Oct 21, 2026 · NCT06834282

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

  • Clinical Trial Site, Duarte
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Oct 21, 2026 · NCT07211958

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06543381

A Study of Revumenib and Mezigdomide in People With Leukemia

  • City of Hope Cancer Center (Data collection only), Duarte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 20, 2026 · NCT07356154

Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 2 and older · All sexes · Updated Oct 19, 2026 · NCT06575296

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

  • City of Hope National Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06846606

Niclosamide in Pediatric Patients With Relapsed and Refractory AML

  • Stanford University, Palo Alto
RecruitingPhase 1
Ages 2 to 30 · All sexes · Updated Oct 14, 2026 · NCT05188170

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • Keck School of Medicine of USC, Los Angeles
  • UC Irvine Health - Chao Family Comprehensive Cancer Center, Orange
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04256317

Individualized AML Treatment

  • City of Hope Medical Center, Duarte
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT07613385

A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

  • Lucile Packard Children's Hospital /ID# 276015, Palo Alto
RecruitingPhase 1
6 Months – 17 Years · All sexes · Updated Oct 5, 2026 · NCT07306832

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06763341

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.