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Acute Myeloid Leukemia clinical trials recruiting in the U.S.

276 studies for Acute Myeloid Leukemia are recruiting participants at sites across the United States.

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

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Recently updated studies

CD70.CAR for AML and Other CD70+ Leukemias

RecruitingPhase 1
Up to age 75 · All sexes · Updated Nov 13, 2026 · NCT06345027

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

RecruitingPhase 1
Ages 65 and older · All sexes · Updated Nov 13, 2026 · NCT06552416

Phase I Study Of PLM-102 In Patients With Relapsed And Refractory Acute Myeloid Leukemia

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07549464

Allogeneic iNKT Cell Therapy (agenT-797) After SCT

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07758218

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07007312

Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT01311258

ATRN-119 in Combination With Decitabine in Patients With TP53-Mutated AML or Higher-Risk MDS

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07617363

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

RecruitingPhase 2
Ages 12 and older · All sexes · Updated Nov 10, 2026 · NCT03589729

A Study of CRD3874-SI in People With Leukemia

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07661095

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT04986657

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT05672147

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT04797767

HPC Offered for PRESERVE Expansion

RecruitingObservational study
Ages 12 to 80 · All sexes · Updated Nov 6, 2026 · NCT07145411

A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07751991

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.