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Alcohol Use Disorder (AUD) clinical trials recruiting in the U.S.
141 studies for Alcohol Use Disorder (AUD) are recruiting participants at sites across the United States.
An alcohol use disorder (AUD) is drinking that causes distress and harm. AUD can range from mild to severe (alcoholism). Learn the signs that you may have a problem with drinking.
Cities with the most studies
- New Haven, CT17 studies
- Washington, DC14 studies
- Baltimore, MD10 studies
- Providence, RI8 studies
- Philadelphia, PA7 studies
- Los Angeles, CA7 studies
- Dallas, TX5 studies
- Portland, OR5 studies
- New York City, NY5 studies
- Columbus, OH5 studies
- Aurora, CO5 studies
- Chicago, IL5 studies
- San Diego, CA5 studies
- Boston, MA5 studies
- Seattle, WA5 studies
- Minneapolis, MN4 studies
- Atlanta, GA4 studies
- Ann Arbor, MI4 studies
- Mountain View, CA4 studies
- Houston, TX4 studies
- Charleston, SC4 studies
- Orlando, FL3 studies
- Cleveland, OH3 studies
- Madison, WI3 studies
- Miami, FL3 studies
- Indianapolis, IN3 studies
- Little Rock, AR3 studies
- Parma, OH3 studies
- Lexington, KY3 studies
- San Francisco, CA3 studies
By state
- Alabama3 studies
- Arizona4 studies
- Arkansas4 studies
- California15 studies
- Colorado6 studies
- Connecticut19 studies
- Florida6 studies
- Georgia5 studies
- Illinois7 studies
- Indiana4 studies
- Kentucky5 studies
- Maryland23 studies
- Massachusetts8 studies
- Michigan8 studies
- Minnesota4 studies
- New York10 studies
- Ohio11 studies
- Oklahoma3 studies
- Oregon6 studies
- Pennsylvania9 studies
- Rhode Island8 studies
- South Carolina5 studies
- Texas11 studies
- Utah3 studies
- Virginia4 studies
- Washington8 studies
- Wisconsin3 studies
Recently updated studies
Hepatic Lipid Metabolism-Alcohol Use Disorder
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT07191561tAN for Substance Use Disorder
Recruiting
Ages 18 to 64 · All sexes · Updated Sep 28, 2026 · NCT07281261SMART-r: Substance Monitoring and Active Relapse Tracking Repository
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Sep 28, 2026 · NCT06676059Environment and Alcohol: A Pilot Study
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 100 · All sexes · Updated Sep 28, 2026 · NCT06860607Greek Connections Study
RecruitingHealthy volunteers welcome
Ages 18 to 29 · All sexes · Updated Sep 24, 2026 · NCT07839026A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07219966A Study of Brenipatide in Participants With Alcohol Use Disorder
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07219953Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT07218354A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05619185Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT07214207Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
RecruitingPhase 1
Ages 21 to 65 · All sexes · Updated Sep 21, 2026 · NCT06335407Spironolactone in Alcohol Use Disorder (SAUD)
RecruitingPhase 1
Ages 21 to 99 · All sexes · Updated Sep 21, 2026 · NCT05807139PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Sep 18, 2026 · NCT06795581Imaging Mitochondrial Complex-I in Alcohol Use Disorder
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 17, 2026 · NCT07825818Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07824089PT150 Drug for Use in Alcohol Use Disorder
RecruitingPhase 1
Ages 21 to 55 · All sexes · Updated Sep 16, 2026 · NCT06712602Cannabidiol and Alcohol Use Disorder Phenotypes
RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Sep 16, 2026 · NCT07279558Characterization Imaging Instruments in Alcoholics and Non-Alcoholics
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT02108080The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06319872Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 15, 2026 · NCT05677321Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06518785The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
RecruitingPhase 1
Ages 21 to 65 · All sexes · Updated Sep 10, 2026 · NCT06070649Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)
Recruiting
Ages 18 to 86 · All sexes · Updated Sep 9, 2026 · NCT07216872Investigating the Mu:Kappa Opioid Receptor Imbalance in Alcohol Use Disorder
RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 to 70 · All sexes · Updated Sep 9, 2026 · NCT05957159Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
RecruitingObservational study
Ages 21 to 79 · All sexes · Updated Sep 4, 2026 · NCT06864819From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.