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Alcohol Use Disorder (AUD) clinical trials recruiting in the U.S.
138 studies for Alcohol Use Disorder (AUD) are recruiting participants at sites across the United States.
An alcohol use disorder (AUD) is drinking that causes distress and harm. AUD can range from mild to severe (alcoholism). Learn the signs that you may have a problem with drinking.
Cities with the most studies
- New Haven, CT18 studies
- Washington, DC12 studies
- Baltimore, MD10 studies
- Providence, RI7 studies
- Philadelphia, PA6 studies
- Columbus, OH5 studies
- New York City, NY5 studies
- Charleston, SC5 studies
- Aurora, CO5 studies
- Atlanta, GA4 studies
- Los Angeles, CA4 studies
- Minneapolis, MN4 studies
- Seattle, WA4 studies
- Portland, OR4 studies
- Dallas, TX4 studies
- Mountain View, CA4 studies
- Lexington, KY3 studies
- Indianapolis, IN3 studies
- Boston, MA3 studies
- Ann Arbor, MI3 studies
- San Diego, CA3 studies
- Chicago, IL3 studies
- Madison, WI3 studies
- Cleveland, OH3 studies
- Houston, TX3 studies
By state
- California12 studies
- Colorado5 studies
- Connecticut19 studies
- Florida4 studies
- Georgia5 studies
- Illinois5 studies
- Indiana4 studies
- Kentucky5 studies
- Maryland22 studies
- Massachusetts5 studies
- Michigan7 studies
- Minnesota4 studies
- New York8 studies
- Ohio9 studies
- Oregon5 studies
- Pennsylvania8 studies
- Rhode Island7 studies
- South Carolina6 studies
- Texas10 studies
- Washington7 studies
- Wisconsin3 studies
Recently updated studies
Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)
Recruiting
Ages 18 to 86 · All sexes · Updated Nov 13, 2026 · NCT07216872SMART-r: Substance Monitoring and Active Relapse Tracking Repository
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Nov 13, 2026 · NCT06676059Environment and Alcohol: A Pilot Study
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 100 · All sexes · Updated Nov 13, 2026 · NCT06860607Sex Differences in the Response to Abstinence From Alcohol.
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 35 · All sexes · Updated Nov 12, 2026 · NCT03827460Spironolactone in Alcohol Use Disorder (SAUD)
RecruitingPhase 1
Ages 21 to 99 · All sexes · Updated Nov 9, 2026 · NCT05807139NIAAA Natural History Protocol
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 5, 2026 · NCT02231840Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder
RecruitingPhase 2/3
Ages 18 to 65 · All sexes · Updated Nov 5, 2026 · NCT06559995Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
RecruitingPhase 1
Ages 18 to 68 · All sexes · Updated Nov 4, 2026 · NCT07772960Imaging Mitochondrial Complex-I in Alcohol Use Disorder
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Nov 3, 2026 · NCT07825818Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving
RecruitingPhase 2/3
Ages 21 to 65 · All sexes · Updated Nov 3, 2026 · NCT07148843Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder
RecruitingPhase 4
Ages 21 to 65 · All sexes · Updated Nov 2, 2026 · NCT06269627Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)
RecruitingPhase 1
Ages 21 to 70 · All sexes · Updated Nov 2, 2026 · NCT07027839Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder
RecruitingPhase 2Healthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Oct 30, 2026 · NCT07029529Tdcs And cogNitive traininG cOmbined for AUD (TANGO)
Recruiting
Ages 18 to 65 · All sexes · Updated Oct 30, 2026 · NCT05062369Developing a Novel Human Laboratory Paradigm for AUD Medication Screening
RecruitingHealthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Oct 30, 2026 · NCT06489782Peer Support for Liver Transplant Recipients With History of ALD
Recruiting
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07397598PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Oct 27, 2026 · NCT06795581Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder
RecruitingPhase 2/3
Ages 21 to 65 · All sexes · Updated Oct 21, 2026 · NCT06807918A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT05619185Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Oct 19, 2026 · NCT06484075AAT for Alcohol Use Disorder in Veterans
Recruiting
Ages 18 to 65 · All sexes · Updated Oct 16, 2026 · NCT05372029Suvorexant for Treatment of AUD and PTSD
RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Oct 14, 2026 · NCT06679062Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)
RecruitingPhase 1
Ages 21 to 65 · All sexes · Updated Oct 13, 2026 · NCT07559500Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Oct 13, 2026 · NCT05677321Hepatic Lipid Metabolism-Alcohol Use Disorder
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Oct 8, 2026 · NCT07191561From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.