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Anhedonia clinical trials recruiting in the U.S.

19 studies for Anhedonia are recruiting participants at sites across the United States.

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Recently updated studies

Psilocybin as a Novel Therapy for Residual Anhedonia

RecruitingPhase 1
Ages 18 to 65 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07607938

Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Aug 31, 2026 ยท NCT06132581

Valuation in Depressed Mood, Anhedonia, and Anxiety

Recruiting
Ages 25 to 50 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT05384158

Reward Sensitivity Digital Intervention for Suicide Risk

Recruiting
Ages 13 to 17 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT07661901

Stress Trajectories and Anhedonia in Adolescence Research Study

RecruitingHealthy volunteers welcome
Ages 13 to 15 ยท All sexes ยท Updated Aug 17, 2026 ยท NCT07040449

A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

Recruiting
Ages 13 to 24 ยท All sexes ยท Updated Aug 12, 2026 ยท NCT07348666

Determining the Role of Social Reward Learning in Social Anhedonia

Recruiting
Ages 18 to 35 ยท All sexes ยท Updated Jul 27, 2026 ยท NCT05617898

Get ActivE Study for At-risk Youth

Recruiting
Ages 12 to 18 ยท All sexes ยท Updated Jun 4, 2026 ยท NCT06829953

Inflammation and Depression in People With HIV

RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated May 28, 2026 ยท NCT05849038

Geolocation Positional System (GPS) Experience

RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated May 5, 2026 ยท NCT05991713

Psychotherapy Effects on Reward Processing in PTSD

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated May 1, 2026 ยท NCT06096740

Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia

Recruiting
Ages 22 to 75 ยท All sexes ยท Updated May 1, 2026 ยท NCT06982820

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

RecruitingPhase 4
Ages 45 to 55 ยท Women ยท Updated Apr 29, 2026 ยท NCT05282277

Neutralizing Interleukin (IL)-6

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Apr 29, 2026 ยท NCT07493317

Reward Processing and Exposure Therapy for Social Anxiety Disorder

Recruiting
Ages 18 to 60 ยท All sexes ยท Updated Apr 2, 2026 ยท NCT06776991

A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide

Recruiting
Ages 13 to 18 ยท All sexes ยท Updated Mar 4, 2026 ยท NCT05920252

Dopaminergic Therapy for Anhedonia - 2

RecruitingPhase 4
Ages 25 to 55 ยท All sexes ยท Updated Jan 28, 2026 ยท NCT06075771

Virtual Incentive Treatment for Alcohol

Recruiting
Ages 18 and older ยท All sexes ยท Updated May 30, 2025 ยท NCT06265506

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.