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Anhedonia clinical trials recruiting in the U.S.
19 studies for Anhedonia are recruiting participants at sites across the United States.
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Recently updated studies
Psilocybin as a Novel Therapy for Residual Anhedonia
RecruitingPhase 1
Ages 18 to 65 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07607938Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Aug 31, 2026 ยท NCT06132581Valuation in Depressed Mood, Anhedonia, and Anxiety
Recruiting
Ages 25 to 50 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT05384158Reward Sensitivity Digital Intervention for Suicide Risk
Recruiting
Ages 13 to 17 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT07661901Stress Trajectories and Anhedonia in Adolescence Research Study
RecruitingHealthy volunteers welcome
Ages 13 to 15 ยท All sexes ยท Updated Aug 17, 2026 ยท NCT07040449A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Recruiting
Ages 13 to 24 ยท All sexes ยท Updated Aug 12, 2026 ยท NCT07348666Determining the Role of Social Reward Learning in Social Anhedonia
Recruiting
Ages 18 to 35 ยท All sexes ยท Updated Jul 27, 2026 ยท NCT05617898Get ActivE Study for At-risk Youth
Recruiting
Ages 12 to 18 ยท All sexes ยท Updated Jun 4, 2026 ยท NCT06829953Inflammation and Depression in People With HIV
RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated May 28, 2026 ยท NCT05849038Geolocation Positional System (GPS) Experience
RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated May 5, 2026 ยท NCT05991713Psychotherapy Effects on Reward Processing in PTSD
Recruiting
Ages 18 to 65 ยท All sexes ยท Updated May 1, 2026 ยท NCT06096740Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia
Recruiting
Ages 22 to 75 ยท All sexes ยท Updated May 1, 2026 ยท NCT06982820Examining the Effects of Estradiol on Neural and Molecular Response to Reward
RecruitingPhase 4
Ages 45 to 55 ยท Women ยท Updated Apr 29, 2026 ยท NCT05282277Neutralizing Interleukin (IL)-6
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Apr 29, 2026 ยท NCT07493317Reward Processing and Exposure Therapy for Social Anxiety Disorder
Recruiting
Ages 18 to 60 ยท All sexes ยท Updated Apr 2, 2026 ยท NCT06776991A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Recruiting
Ages 13 to 18 ยท All sexes ยท Updated Mar 4, 2026 ยท NCT05920252Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression
Recruiting
Ages 18 to 50 ยท All sexes ยท Updated Feb 18, 2026 ยท NCT05240352Dopaminergic Therapy for Anhedonia - 2
RecruitingPhase 4
Ages 25 to 55 ยท All sexes ยท Updated Jan 28, 2026 ยท NCT06075771Virtual Incentive Treatment for Alcohol
Recruiting
Ages 18 and older ยท All sexes ยท Updated May 30, 2025 ยท NCT06265506From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.