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Ankle Injuries and Disorders clinical trials recruiting in the U.S.
16 studies for Ankle Injuries and Disorders are recruiting participants at sites across the United States.
Ankle injuries and ankle disorders can affect tendons and cartilage. Learn about different kinds of ankle problems including sprains and fractures.
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Recently updated studies
Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures
Recruiting
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT03966027Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability
RecruitingHealthy volunteers welcome
Ages 18 to 45 · All sexes · Updated Jul 21, 2026 · NCT06868316Simplified Post Op Rehabilitation for Ankle and Pilon Fractures
Recruiting
Ages 18 to 65 · All sexes · Updated Jun 8, 2026 · NCT05280639Semiconductor Embedded Socks for Ankle Sprains
Recruiting
Ages 18 to 70 · All sexes · Updated May 1, 2026 · NCT07025733Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT06949826Fibulink Syndesmosis Repair System With Early Full-Weight Bearing
RecruitingHealthy volunteers welcome
Ages 22 and older · All sexes · Updated Mar 20, 2026 · NCT06085586Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients
RecruitingPhase 2
Ages 18 to 95 · All sexes · Updated Mar 9, 2026 · NCT06780202Neuromuscular Electrical Stimulation in Foot and Ankle Surgery
Recruiting
Ages 18 to 70 · All sexes · Updated Feb 27, 2026 · NCT06370325BioBrace® in Arthroscopic Brostrom Lateral Ankle Ligament Repair
Recruiting
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT07401095Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 10, 2026 · NCT05729542Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture
Recruiting
Ages 18 to 50 · All sexes · Updated Dec 2, 2025 · NCT07173088Randomized Controlled Trial for Ankle Fracture Pain Control
RecruitingPhase 4
Ages 18 to 89 · All sexes · Updated Nov 6, 2025 · NCT03696199Dance Mental Health App
Recruiting
Ages 13 to 18 · All sexes · Updated Oct 21, 2025 · NCT07219095A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability
Recruiting
Ages 18 to 49 · All sexes · Updated Jul 18, 2025 · NCT04999904Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery
Recruiting
Ages 18 to 89 · All sexes · Updated Mar 24, 2025 · NCT05445960Opioid-Free Pain Treatment in Trauma Patients
Recruiting
Ages 18 and older · All sexes · Updated Oct 26, 2024 · NCT06078371From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.