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Semiconductor Embedded Socks for Ankle Sprains

Clinical Outcomes Related to Treatment of Ankle Injury Using Semiconductor Embedded Therapeutic Socks: A Randomized, Prospective, Double Blinded Clinical Study

Who can join

Ages 18 to 70 · All sexes

Inclusion Criteria:

* Ankle sprain, avulsion fracture, distal fibular fracture
* Pain for at least 1 day
* Patients 18-69 years old

Exclusion Criteria:

* Patients with neurological conditions
* Patients with prior surgical treatment of lower limb injury
* Patients with chronic pain conditions
* Patient with auto-immune or auto-inflammatory disease
* Patients with tobacco use in last 90 days
* Patients with history of metabolic disorders
* Patients with open wound at area of application
* Patients with acute or systemic infection

About the study

The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains. The main questions it aims to answer are:

1. How does semiconductor embedded sock effect outcomes in patients undergoing rehabilitation from ankle injury? 2. How does semiconductor embedded socks effect injury symptoms and function throughout the course of treatment?

Researchers will compare semiconductor embedded socks with typical compression socks to determine differences in healing.

Participants will be given the socks and be asked to wear them throughout the healing process and record symptoms and functional measures.

What is being tested

• Semiconductor Embedded Sock (device)
• Control Compression Sock (device)

Sponsor: University of Colorado, Denver · Participants: 100 · Started: Apr 10, 2025

Contact the study team

• Study Coordinator · Phone: 3037243185

Official record on ClinicalTrials.gov — NCT07025733

Locations in the U.S.

Conditions

• Ankle Injuries and Disorders

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.