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Birth Defects clinical trials recruiting in the U.S.
21 studies for Birth Defects are recruiting participants at sites across the United States.
A birth defect is a problem that happens while a baby is developing in the mother's body. Learn about the different types of birth defects, their treatments, and how some kinds can be prevented.
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Recently updated studies
Genome Medical Sequencing for Gene Discovery
RecruitingObservational study
4 Weeks – 99 Years · All sexes · Updated Sep 28, 2026 · NCT01087320MRI Study of Musculoskeletal Function
RecruitingObservational studyHealthy volunteers welcome
Ages 5 to 95 · All sexes · Updated Sep 22, 2026 · NCT00051857An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 70 · All sexes · Updated Sep 22, 2026 · NCT00001595Data Collection Study of Pediatric and Adolescent Gynecology Conditions
RecruitingObservational studyHealthy volunteers welcome
1 Day – 100 Years · All sexes · Updated Aug 6, 2026 · NCT04717349Human Penile Allotransplantation
RecruitingPhase 2/3
Ages 18 to 69 · Men · Updated Jul 14, 2026 · NCT02395497Registry of Older Patients With Cancer
RecruitingObservational study
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
RecruitingObservational study
All ages · All sexes · Updated Jun 22, 2026 · NCT02432079Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06989593Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH
Recruiting
Ages 18 and older · Women · Updated Apr 23, 2026 · NCT07166172Genetics of Congenital Heart Disease
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 7, 2026 · NCT01192048Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
RecruitingObservational study
Ages 18 and older · Women · Updated Mar 4, 2026 · NCT03775954Impact of Hospital to Home: Optimizing Preterm Infant Environment for Surgical Neonates and Their Parents (H-HOPE)
Recruiting
1 Week – 8 Weeks · All sexes · Updated Jan 28, 2026 · NCT07372898Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
RecruitingPhase 1
All ages · All sexes · Updated Nov 12, 2025 · NCT03723564Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 27, 2025 · NCT01137643OPT-IN: Osteopathic Plagiocephaly Treatment for Infants and Neonates
Recruiting
1 Day – 4 Months · All sexes · Updated Aug 3, 2025 · NCT05848895The Heartland Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · Women · Updated Jun 29, 2025 · NCT05492708Prospective Evaluation of Treatment for Clubfoot
RecruitingObservational study
Up to age 18 · All sexes · Updated May 4, 2025 · NCT02257229Genetic Inclusion by Virtual Evaluation
RecruitingHealthy volunteers welcome
1 Day – 18 Years · All sexes · Updated Jan 30, 2025 · NCT05318222Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
RecruitingObservational study
All ages · Women · Updated Jan 28, 2025 · NCT02103361Pregnancies Complicated by Fetal Anomalies
RecruitingObservational study
1 Minute – 50 Years · All sexes · Updated Dec 9, 2024 · NCT02505464Treatment of Brain AVMs (TOBAS) Study
Recruiting
Ages 5 and older · All sexes · Updated Aug 15, 2024 · NCT02098252From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.