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Brain Diseases clinical trials recruiting in the U.S.

45 studies for Brain Diseases are recruiting participants at sites across the United States.

Brain diseases affect different functions of the body from memory, speech, thinking clearly, how well the different organs work, or even movement.

Cities with the most studies

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Recently updated studies

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Nov 12, 2026 · NCT06887192

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Recruiting
Ages 18 to 75 · All sexes · Updated Nov 12, 2026 · NCT07056361

Inflammatory and Infectious Diseases of the Nervous System

RecruitingObservational study
Ages 2 to 110 · All sexes · Updated Nov 9, 2026 · NCT02435810

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

RecruitingObservational study
7 Months – 15 Months · All sexes · Updated Nov 5, 2026 · NCT06805695

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 4, 2026 · NCT07589595

CoMind Early Feasibility Study

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06368648

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Oct 29, 2026 · NCT06297590

Natural History of Stroke: Cause and Development

RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 26, 2026 · NCT00009243

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Oct 15, 2026 · NCT07459647

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Recruiting
Ages 50 and older · All sexes · Updated Oct 15, 2026 · NCT06993142

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT05386108

Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU

Recruiting
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT07219108

Pediatric Epilepsy

Recruiting
Ages 3 to 25 · All sexes · Updated Oct 6, 2026 · NCT07350551

kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot

Recruiting
Ages 18 to 80 · All sexes · Updated Sep 29, 2026 · NCT07631078

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 29, 2026 · NCT06615973

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT07056348

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

Brain Development Research Program

RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT00305305

Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)

RecruitingPhase 1
Ages 40 to 75 · All sexes · Updated Aug 17, 2026 · NCT06482268

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05812755

Neonatal Neurological Observation With Video AI

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Jul 15, 2026 · NCT07628829

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

RecruitingPhase 1/2
Ages 35 to 85 · All sexes · Updated Jul 10, 2026 · NCT05462106

Auricular VNS Following Intracerebral Hemorrhage

Recruiting
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06799390

F 18 T807 Tau PET Imaging of Alzheimer's Disease

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT02414347

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.