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Brain Tumors clinical trials in Maryland

18 studies for Brain Tumors are looking for participants at sites in Maryland.

Cities in Maryland

Evaluation and Treatment of Neurosurgical Disorders

  • National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 4 to 99 · All sexes · Updated Sep 29, 2026 · NCT00060541

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1/2
Ages 18 to 99 · All sexes · Updated Sep 28, 2026 · NCT07416188

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

  • Johns Hopkins Sidney Kimmel Cancer Center - Baltimore, Baltimore
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

  • Johns Hopkins Hospital, Baltimore
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Tumor Related Epilepsy

  • National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 8 to 99 · All sexes · Updated Aug 28, 2026 · NCT02639325

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1/2
Ages 15 and older · All sexes · Updated Aug 28, 2026 · NCT05588141

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

  • The Johns Hopkins Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06764940

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

  • University of Maryland, Baltimore
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Aug 19, 2026 · NCT05317858

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

  • NIH Clinical Center, Bethesda
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT03750227

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1/2
Ages 18 to 120 · All sexes · Updated Aug 12, 2026 · NCT06161519

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

  • Johns Hopkins Hospital, Baltimore
Recruiting
Up to age 39 · All sexes · Updated Jul 13, 2026 · NCT06796543

Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

  • Johns Hopkins Hospital, Baltimore
RecruitingHealthy volunteers welcome
Ages 1 to 26 · All sexes · Updated Jun 29, 2026 · NCT05658731

REMASTer: REcurrent Brain Metastases After SRS Trial

  • University of Maryland, Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05124912

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

  • Walter Reed National Military Medical Center, Bethesda
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT03550391

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

  • Maryland Proton Treatment Center, Baltimore
  • University of Maryland Greenebaum Cancer Center, Baltimore
  • UCH Kaufman Cancer Center, Bel Air
  • and 2 more
Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT04699773

Precision Radiotherapy Enabled by Molecular MRI

  • Johns Hopkins University, Baltimore
Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07512154

Pediatric Radiation Therapy Registry

  • Johns Hopkins Hospital, Baltimore
RecruitingObservational study
Ages 0 to 26 · All sexes · Updated Nov 5, 2025 · NCT07129317

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

  • UM Upper Chesapeake Medical Center, Bel Air
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.