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Brain Tumors clinical trials in Minnesota

19 studies for Brain Tumors are looking for participants at sites in Minnesota.

Cities in Minnesota

Extracellular Impact of Ultrasound-induced Blood-brain Barrier Disruption

  • Mayo Clinic Minnesota, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05733312

REMIND Maintenance Radiotherapy for Newly Diagnosed Glioblastoma

  • University of Minnesota Radiation Oncology, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07831772

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

  • Local Institution - 0129, Rochester
  • Local Institution - 0174, Rochester
  • Local Institution - 0181, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

  • Masonic Cancer Center University of Minnesota, Minneapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

  • Children's Hospital and Clinics of Minnesota, Minneapolis
RecruitingPhase 2
59 Months · All sexes · Updated Sep 15, 2026 · NCT05535166

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

  • Minnesota Oncology - Burnsville, Burnsville
  • Cambridge Medical Center, Cambridge
  • Mercy Hospital, Coon Rapids
  • and 21 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

  • Mayo Clinic in Rochester, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT03750227

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions

  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT04047264

Ommaya Reservoir Placement for Brain Tumor Biomarker Access

  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT04692337

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06322602

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

  • Abbott Northwestern Hospital, Minneapolis
  • University of Minnesota, Minneapolis
RecruitingObservational study
All ages · All sexes · Updated Jul 22, 2026 · NCT04427384

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

  • Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06377696

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

  • University of Minnesota, Minneapolis
Recruiting
Up to age 39 · All sexes · Updated Jul 13, 2026 · NCT06796543

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

  • Mayo Clinic in Rochester, Rochester
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Jun 10, 2026 · NCT06788886

An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

  • Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06667726

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

  • Mayo Clinic Health System in Albert Lea, Albert Lea
  • Mayo Clinic Health Systems-Mankato, Mankato
  • Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05222620

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

  • Mayo Clinic Cancer Center, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Allina Health Cancer Institute, Minneapolis
  • Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

  • Mercy Hospital, Coon Rapids
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood
  • Abbott-Northwestern Hospital, Minneapolis
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.