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Cancer (all types) clinical trials in North Carolina
92 studies for Cancer (all types) are looking for participants at sites in North Carolina.
Cities in North Carolina
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Messino Cancer Centers Asheville, Asheville
- Duke University Medical Center Duke Cancer Center, Durham
- FirstHealth Cancer Center, Pinehurst
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Nov 13, 2026 · NCT05920356Bexmarilimab + Azacitidine Versus Placebo + Azacitidine in Participants With Treatment-naïve Higher-risk Myelodysplastic Syndromes
- University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07672769Feasibility Pilot of AYA-PARTNER
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 to 39 · All sexes · Updated Nov 12, 2026 · NCT07829146A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
- University of North Carolina /ID# 251203, Chapel Hill
- Atrium Health Wake Forest Baptist Medical Center /ID# 251165, Winston-Salem
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT05650632RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 10, 2026 · NCT07002034Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
- Duke University Medical Center, Durham
- Duke Women's Cancer Care Raleigh, Raleigh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06580314Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
- East Carolina University, Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07195591A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
- University of North Carolina at Chapel Hill, Chapel Hill
- Duke University Medical Center - Duke Cancer Centre, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06901531Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
- Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill, Chapel Hill
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06096038A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
- Oncology Specialists of Charlotte, Charlotte
- Southern Oncology Specialists, Huntersville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07169851A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- Levine Cancer Institute, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06150157Distance-Based Exercise to Preserve Function and Prevent Disability
- Novant Health Cancer Institute - Kernersville, Kernersville
- Novant Health Cancer Institute - Mount Airy, Mount Airy
- Novant Health Forsyth Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- University of North Carolina Medical Center, Chapel Hill
- Duke Cancer Institute, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06119581Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
- Atrium Health Carolinas Medical Center, Charlotte
- Duke Health - Duke University Hospital, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05856981Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- The University of North Carolina at Chapel Hill, Chapel Hill
- Levine Cancer Institute, Charlotte
- Duke University Medical Center, Durham
- and 1 more
RecruitingPhase 2/3
All ages · All sexes · Updated Nov 2, 2026 · NCT03435796A Study of ARC-02 in B-cell NHL
- Levine Cancer Institute, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07691606A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
- GSK Investigational Site, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06796907Young Adult Infusion Space Experience Satisfaction Survey
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingObservational study
Ages 18 to 39 · All sexes · Updated Nov 2, 2026 · NCT05720546Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed Cancer
- Duke University, Durham
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07811258Keep Social Randomized Controlled Trial for Young Adults With Cancer
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 22 to 39 · All sexes · Updated Oct 30, 2026 · NCT07788339Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 3
Ages 18 to 71 · All sexes · Updated Oct 30, 2026 · NCT07504458A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)
- Atrium Health Levine Cancer, Charlotte
- Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07614022Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 28, 2026 · NCT01137643Comprehensive Care for AYA: Needs Assessment Survey
- Atrium Health Levine Cancer, Charlotte
- Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingObservational study
Ages 15 and older · All sexes · Updated Oct 27, 2026 · NCT07196241Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer
- FirstHealth Cancer Center, Pinehurst
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT05168566A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
- Atrium Health Levine Cancer Institute /ID# 271510, Charlotte
- University Of North Carolina Health Care - Hillsborough Campus /ID# 272454, Hillsborough
- Atrium Health Wake Forest Baptist Medical Center /ID# 271294, Winston-Salem
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06953960Study of the Effect of Innate on the Inflammatory Response to Endotoxin
- NIEHS Clinical Research Unit (CRU), Research Triangle Park
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Oct 26, 2026 · NCT01143480A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
- Research Site, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06835569Neurocognitive Trajectories After BCMA CAR-T
- Atrium Health Levine Cancer, Charlotte
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07740317Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
- Durham VA Medical Center, Durham, NC, Durham
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT02984761UNC Pleural Fluid Registry
- UNC Lingeberger Comprehensive Cancer Center, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT05620329A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
- Duke Cancer Center, Durham
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 20, 2026 · NCT07103018A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
- University of North Carolina at Chapel Hill /ID# 274667, Chapel Hill
- Atrium Health Levine Cancer Institute /ID# 276193, Charlotte
- Atrium Health Wake Forest Baptist Medical Center /ID# 274847, Winston-Salem
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT06892522A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
- UNC Hospitals, The University of North Carolina at Chapel Hill, Chapel Hill
- Levine Cancer Institute, Charlotte
- University of North Carolina Hospitals at Hillsborough, Hillsborough
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06989437A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
- Research Site, Charlotte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05123482Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
- Carolina BioOncology Institute, Huntersville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06993844A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
- Duke University Medical Center /ID# 279457, Durham
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT07023289FOG-001 in Locally Advanced or Metastatic Solid Tumors
- Duke University, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT05919264CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
- Duke University Medical Center, Duke Cancer Center, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT03328078A Study of PHN-012 in Patients With Advanced Solid Tumors
- PHN-012-001 Site, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.