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Cancer (all types) clinical trials in Durham, NC
61 studies for Cancer (all types) are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.
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A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
RecruitingPhase 3
- Duke University Medical Center Duke Cancer Center, Durham
Bexmarilimab + Azacitidine Versus Placebo + Azacitidine in Participants With Treatment-naïve Higher-risk Myelodysplastic Syndromes
RecruitingPhase 2
- University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Feasibility Pilot of AYA-PARTNER
Recruiting
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
RecruitingPhase 1
- University of North Carolina /ID# 251203, Chapel Hill · 10 mi away
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
RecruitingPhase 2
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
RecruitingPhase 3
- Duke University Medical Center, Durham
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
RecruitingPhase 3
- Duke University Medical Center - Duke Cancer Centre, Durham
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
RecruitingPhase 1
- Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill, Chapel Hill · 10 mi away
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
RecruitingPhase 3
- Duke Cancer Institute, Durham
- University of North Carolina Medical Center, Chapel Hill · 10 mi away
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
RecruitingPhase 1
- Duke Health - Duke University Hospital, Durham
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
RecruitingPhase 2/3
- Duke University Medical Center, Durham
- The University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
RecruitingPhase 1/2
- GSK Investigational Site, Durham
Young Adult Infusion Space Experience Satisfaction Survey
RecruitingObservational study
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Improving Adherence to Chronic Disease Medication Regimens Among Patients With Recently Diagnosed Cancer
Recruiting
- Duke University, Durham
Keep Social Randomized Controlled Trial for Young Adults With Cancer
Recruiting
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
RecruitingPhase 3
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
RecruitingObservational study
- Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
RecruitingPhase 1/2
- University Of North Carolina Health Care - Hillsborough Campus /ID# 272454, Hillsborough · 13 mi away
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
RecruitingObservational studyHealthy volunteers welcome
- NIEHS Clinical Research Unit (CRU), Research Triangle Park · 7 mi away
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
RecruitingPhase 1
- Research Site, Durham
Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
Recruiting
- Durham VA Medical Center, Durham, NC, Durham
UNC Pleural Fluid Registry
RecruitingObservational study
- UNC Lingeberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
RecruitingPhase 1
- Duke Cancer Center, Durham
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
RecruitingPhase 1/2
- University of North Carolina at Chapel Hill /ID# 274667, Chapel Hill · 10 mi away
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
- UNC Hospitals, The University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
- University of North Carolina Hospitals at Hillsborough, Hillsborough · 13 mi away
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
RecruitingPhase 2
- Duke University Medical Center /ID# 279457, Durham
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Duke University, Durham
CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
RecruitingPhase 1/2
- Duke University Medical Center, Duke Cancer Center, Durham
A Study of PHN-012 in Patients With Advanced Solid Tumors
RecruitingPhase 1
- PHN-012-001 Site, Durham
uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
RecruitingObservational study
- The University of North Carolina Chapel Hill, Chapel Hill · 10 mi away
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
RecruitingPhase 2
- Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
A Phase 1/1b Study of IAM1363 in HER2 Cancers
RecruitingPhase 1
- Duke Cancer Institute, Durham
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
RecruitingPhase 3
- Duke Cancer Center, Durham
Project: Every Child for Younger Patients With Cancer
RecruitingObservational study
- Duke University Medical Center, Durham
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
Recruiting
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Abatacept in Immune Checkpoint Inhibitor Myocarditis
RecruitingPhase 3
- University of North Carolina Chapel Hill, Chapel Hill · 10 mi away
Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
RecruitingPhase 1
- Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Behavioral Pain Intervention for Older Cancer Patients
Recruiting
- Duke Cancer Network, Durham
A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
RecruitingPhase 1
- Duke Cancer Institute, Durham
A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers
Recruiting
- University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology
RecruitingHealthy volunteers welcome
- University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill · 10 mi away
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
- Durham VA Medical Center, Durham, NC, Durham
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
RecruitingObservational study
- University of North Carolina, Chapel Hill · 10 mi away
Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
RecruitingPhase 1
- Duke Cancer Center /ID# 251975, Durham
Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
RecruitingPhase 2
- Duke Comprehensive Cancer Center, Durham
- University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery
Recruiting
- Durham VA Medical Center, Durham, NC, Durham
Improving Outcomes in Early Menopause After Cancer
Recruiting
- Duke Cancer Institute, Durham
UNC Childhood, Adolescent, and Young Adult Cancer Cohort
RecruitingObservational study
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors
RecruitingHealthy volunteers welcome
- Duke Cancer Institute, Durham
UNC Metastatic Cancer Radiation Therapy Registry
RecruitingObservational study
- Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill · 10 mi away
Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine Tumors
RecruitingObservational study
- UNC Hospitals, Chapel Hill · 10 mi away
Rehabilitation Outcomes Study
Recruiting
- The N.C. Cancer Hospital, Chapel Hill · 10 mi away
Cancer and Mild Cognitive Impairment Dyadic Intervention
Recruiting
- Duke University, Durham
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
RecruitingPhase 2
- University of North Carolina /ID# 233313, Chapel Hill · 10 mi away
GEMINI-NSCLC: NSCLC Biomarker Study
RecruitingObservational study
- Duke University, Durham
- UNC, Chapel Hill · 10 mi away
Effectiveness of Central Oncology Navigation and the Use of an ORN
Recruiting
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
Recruiting
- Duke Cancer Institute, Durham
Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)
Recruiting
- Duke University School of Medicine, Durham
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
A Study of NX-1607 in Adults With Advanced Malignancies
RecruitingPhase 1
- University of North Carolina, Chapel Hill · 10 mi away
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
- Duke University Medical Center, Durham
- University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
- University of North Carolina Hospitals - Hillsborough Campus, Hillsborough · 13 mi away
About Cancer (all types)
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Cancer (all types) trials in other cities
- Houston, TX124 studies
- New York City, NY105 studies
- Boston, MA90 studies
- Los Angeles, CA73 studies
- Nashville, TN65 studies
- Washington, DC60 studies
- Philadelphia, PA57 studies
- Arlington, VA52 studies
- Chicago, IL51 studies
- St. Louis, MO51 studies
- Atlanta, GA49 studies
- Seattle, WA48 studies
Other studies in Durham
- Breast Cancer63 studies
- Non-Small Cell Lung Cancer42 studies
- Multiple Myeloma36 studies
- Acute Myeloid Leukemia34 studies
- Lung Cancer33 studies
- Metastatic Cancer33 studies
- Prostate Cancer32 studies
- Colorectal Cancer30 studies
- Ovarian Cancer28 studies
- Chronic Lymphocytic Leukemia28 studies
- Heart Failure25 studies
- Pancreatic Cancer24 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.