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Cardiovascular Disease clinical trials in Minnesota
30 studies for Cardiovascular Disease are looking for participants at sites in Minnesota.
Cities in Minnesota
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
- Clinical Trial Site, Richfield
- Clinical Trial Site, Saint Cloud
- Clinical Trial Site, Saint Paul
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07181109INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
- Abbott Northwestern, Minneapolis
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT06965504A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
- Minneapolis Heart Institute, Minneapolis
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07286578VDyne TriNova Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
- Minneapolis Heart Institute, Minneapolis
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07516444Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
- Mayo Clinic, Rochester
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07601425Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Minneapolis Heart Institute, Minneapolis
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195ELEVATE-HFpEF Clinical Study
- M Health Fairview University of Minnesota Medical Center - East Bank, Minneapolis
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
- Abbott Northwestern Hospital, Minneapolis
- M Health Fairview University of Minnesota Medical Center - East Bank, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT03242642Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
- Aspirus Saint Luke's Hospital, Duluth
- Essentia Health-SMMC, Duluth
- JAVARA Inc, - Mankato Clinic, Mankato
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06909565The TRICURE EFS Study
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06506942Product Surveillance Registry
- Coon Rapids
- Minneapolis
- Robbinsdale
- and 1 more
RecruitingObservational study
All ages · All sexes · Updated Oct 20, 2026 · NCT01524276Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
- University of Minnesota, Minneapolis
RecruitingEarly phase 1
Ages 60 and older · All sexes · Updated Oct 20, 2026 · NCT06507657Global Paradise System US Post Approval Study
- Metropolitan Heart & Vascular Institute, Coon Rapids
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06297291CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
- Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05931276Zenith® Fenestrated+ Clinical Study
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04875429A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
- Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338Obstructive Sleep Apnea Among Somali-Americans
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT04124848Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Essentia Health, Duluth
- Mayo Clinic, Rochester
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
- Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
- Research Site, Duluth
- Research Site, Minneapolis
- Research Site, Minneapolis
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- Saint Marys Medical Center, Duluth
- Health East Cancer Care, Maplewood
- University of Minnesota, Minneapolis
- and 2 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012COMPARE-VENT Feasibility Pilot Study
- Mayo Clinic, 1216 Second Street SW, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07656259PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- University of Minnesota, Minneapolis
- Centra Care Heart Center, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Mayo AVC Registry and Biobank
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 27, 2026 · NCT03049254The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- CentraCare Heart and Vascular, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
- Mayo Clinic, Rochester
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06271577CVD/PH and Voice Characteristics
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 30, 2025 · NCT07311044A Study of Mayo Clinic CV Research Heart & Voice Study
- Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT07224685MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
- Metropolitan Heart and Vascular Institute, Coon Rapids
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331PARTNER 3 Trial - Aortic Valve-in-Valve
- Mayo Clinic, Rochester
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.