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Cardiovascular Disease clinical trials recruiting in the U.S.
213 studies for Cardiovascular Disease are recruiting participants at sites across the United States.
Cities with the most studies
- Boston, MA34 studies
- New York City, NY30 studies
- Washington, DC27 studies
- Dallas, TX24 studies
- Houston, TX22 studies
- Philadelphia, PA22 studies
- Pittsburgh, PA21 studies
- St. Louis, MO20 studies
- Cleveland, OH20 studies
- San Francisco, CA20 studies
- Chicago, IL20 studies
- Atlanta, GA20 studies
- Durham, NC19 studies
- Nashville, TN18 studies
- Los Angeles, CA17 studies
- Birmingham, AL16 studies
- Phoenix, AZ16 studies
- Indianapolis, IN16 studies
- Charleston, SC16 studies
- Cincinnati, OH16 studies
- Rochester, MN15 studies
- Ann Arbor, MI15 studies
- Minneapolis, MN15 studies
- Salt Lake City, UT14 studies
- San Diego, CA14 studies
- Portland, OR14 studies
- Richmond, VA13 studies
- Columbus, OH13 studies
- Jacksonville, FL13 studies
- Winston-Salem, NC13 studies
- Tampa, FL13 studies
- Orlando, FL12 studies
- Harrisburg, PA12 studies
- Kansas City, KS12 studies
- Baltimore, MD11 studies
- Tucson, AZ11 studies
- The Bronx, NY11 studies
- Albuquerque, NM11 studies
- Austin, TX11 studies
- Kansas City, MO11 studies
By state
- Alabama21 studies
- Arizona24 studies
- Arkansas7 studies
- California55 studies
- Colorado18 studies
- Connecticut18 studies
- District of Columbia11 studies
- Florida37 studies
- Georgia26 studies
- Idaho5 studies
- Illinois30 studies
- Indiana19 studies
- Iowa8 studies
- Kansas17 studies
- Kentucky15 studies
- Louisiana12 studies
- Maine4 studies
- Maryland27 studies
- Massachusetts36 studies
- Michigan29 studies
- Minnesota30 studies
- Mississippi9 studies
- Missouri26 studies
- Montana3 studies
- Nebraska9 studies
- Nevada7 studies
- New Hampshire4 studies
- New Jersey21 studies
- New Mexico11 studies
- New York39 studies
- North Carolina30 studies
- North Dakota3 studies
- Ohio35 studies
- Oklahoma13 studies
- Oregon15 studies
- Pennsylvania37 studies
- Rhode Island5 studies
- South Carolina21 studies
- South Dakota8 studies
- Tennessee26 studies
- Texas40 studies
- Utah21 studies
- Vermont5 studies
- Virginia23 studies
- Washington14 studies
- West Virginia9 studies
- Wisconsin13 studies
Recently updated studies
Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation
Recruiting
Ages 40 and older · All sexes · Updated Nov 13, 2026 · NCT06938412Community Health Worker-Led Intervention to Increase Cardiac Rehabilitation Participation
Recruiting
Ages 21 and older · All sexes · Updated Nov 12, 2026 · NCT06908590Designing and Assessing a Women Only Cardiac Rehabilitation (CARE) Program
Recruiting
Ages 40 to 80 · Women · Updated Nov 12, 2026 · NCT06784895Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT07258290Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07181109Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Nov 12, 2026 · NCT04216342EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473A Study to Evaluate the Safety and Efficacy of AC01 Compared to Placebo in Participants With Chronic Heart Failure
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Nov 12, 2026 · NCT07584967INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT06965504Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 70 · All sexes · Updated Nov 12, 2026 · NCT03374215A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Nov 10, 2026 · NCT07839936Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Nov 10, 2026 · NCT06001814A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07286578VDyne TriNova Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
Recruiting
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07516444A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
RecruitingPhase 2
All ages · All sexes · Updated Nov 10, 2026 · NCT04467671Gut Microbiota in Metabolic Surgery
RecruitingObservational study
Ages 21 to 65 · All sexes · Updated Nov 9, 2026 · NCT05000996Natural History Study of CADASIL
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 9, 2026 · NCT05072483Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07601425NightWare and Cardiovascular Health in Women With PTSD
RecruitingHealthy volunteers welcome
Ages 22 to 40 · Women · Updated Nov 6, 2026 · NCT07021014Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 30 · All sexes · Updated Nov 5, 2026 · NCT06263452A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
RecruitingPhase 3
Ages 45 to 80 · All sexes · Updated Nov 4, 2026 · NCT07613294A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802ELEVATE-HFpEF Clinical Study
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.