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Cardiovascular Disease clinical trials in South Carolina

21 studies for Cardiovascular Disease are looking for participants at sites in South Carolina.

Cities in South Carolina

ELEVATE-HFpEF Clinical Study

  • Medical University of South Carolina (MUSC), Charleston
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

  • Medical University of South Carolina, Charleston
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Monroe Biomedical Research - Charleston, North Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • Piedmont Research Partners, LLC, Fort Mill
  • Velocity Clinical Research-Gaffney-69046, Gaffney
  • Tribe Clinical Research LLC - Greenville, Greenville
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

Product Surveillance Registry

  • Charleston
  • Columbia
  • Orangeburg
  • and 1 more
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Columbia
  • Clinical Trial Site, Greenville
  • Clinical Trial Site, Greer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Improving the Collaborative Health of Adult Dyads

  • University of South Carolina, Columbia
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05370014

Zenith® Fenestrated+ Clinical Study

  • Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Medical University of South Carolina, Charleston
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

  • Clinical Research Site, Charleston
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Charleston VA Medical Center, Charleston
  • Medical University of South Carolina, Charleston
  • Columbia VA Health Care System/Dorn VA Medical Center, Columbia
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

  • Research Site, Charleston
  • Research Site, Fort Mill
  • Research Site, Mauldin
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

  • Pharmacorp Clinical Trials Inc, Charleston
  • Medical University of South Carolina, Charleston
  • Prisma Health Carolina Cardiology - Greenville, Gantt
  • and 3 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Global Paradise System US Post Approval Study

  • Medical University of South Carolina, Charleston
  • Prisma Health Richland Hospital, Columbia
  • Spartanburg Regional Medical Center, Spartanburg
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Recruiting
Ages 21 and older · All sexes · Updated Jul 27, 2026 · NCT04877197

The TRICURE EFS Study

  • Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Medical University of South Carolina (MUSC), Charleston
  • PRISMA Health- Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Medical University of South Carolina, Charleston
  • Prisma Health Midlands, Columbia
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Pivotal Study for the Cardiac Performance System (CPS)

  • Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

  • Prisma Health, Greenville
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.