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Cholesterol clinical trials recruiting in the U.S.

22 studies for Cholesterol are recruiting participants at sites across the United States.

Your body needs some cholesterol, but too much can raise your risk of heart disease. Know the types (HDL and LDL), and how to lower high cholesterol.

Cities with the most studies

By state

Recently updated studies

Causes and Natural History of Dyslipidemias

RecruitingObservational study
Ages 2 to 100 · All sexes · Updated Sep 29, 2026 · NCT00353782

Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia

Recruiting
All ages · All sexes · Updated Sep 29, 2026 · NCT06743659

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07491172

Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07799961

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

RecruitingPhase 3
Ages 2 to 11 · All sexes · Updated Jul 24, 2026 · NCT06597006

A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Jul 22, 2026 · NCT07477704

Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia

RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Jul 17, 2026 · NCT06451770

Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

Recruiting
Ages 18 to 60 · All sexes · Updated Jul 16, 2026 · NCT06988462

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

RecruitingPhase 3
Ages 6 to 11 · All sexes · Updated May 15, 2026 · NCT06597019

Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile

RecruitingHealthy volunteers welcome
Ages 18 to 74 · All sexes · Updated Apr 17, 2026 · NCT07514663

Pharmacogenomic Informed Statin Prescribing

Recruiting
Ages 40 to 75 · All sexes · Updated Apr 13, 2026 · NCT06568601

Mechanism of Ketogenic Diet-Induced Hypercholesterolemia

RecruitingHealthy volunteers welcome
Ages 18 to 39 · All sexes · Updated Mar 23, 2026 · NCT06894004

Multicomponent Intervention Study- Blood Donors With High Cholesterol

Recruiting
Ages 18 to 75 · All sexes · Updated Mar 17, 2026 · NCT05693701

Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

RecruitingPhase 2
Ages 40 to 75 · All sexes · Updated Feb 27, 2026 · NCT06488105

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

Recruiting
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT06374277

FELLAShip to Better Health

Recruiting
Ages 18 and older · Men · Updated Jan 22, 2026 · NCT07220213

HoFH, the International Clinical Collaborators Registry

RecruitingObservational study
All ages · All sexes · Updated Dec 18, 2025 · NCT04815005

Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 69 · All sexes · Updated Oct 1, 2025 · NCT06747000

Alirocumab in Patients on a Stable Dialysis Regimen

RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Feb 12, 2020 · NCT03480568

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.