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Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia

Alert-Based Computerized Decision Support for Identification and Management of Patients With Familial Hypercholesterolemia (FH-ALERT Trial)

Who can join

All ages · All sexes

Inclusion Criteria:

* ≥ 18 years old
* seen in the BWH Endocrinology, Cardiovascular Medicine, and Primary Care Clinics
* Dutch Lipid Clinic Network score of at least 3 points

Exclusion Criteria:

* a Familial Hypercholesterolemia diagnosis already documented in the EHR medical history, visit history, or problem list

About the study

The goal of this clinical trial is to learn if a computer alert can aid clinicians in identifying patients with a genetic type of high cholesterol, called Familial Hypercholesterolemia. The main question it aims to answer is whether the computer alert increases recognition of this high cholesterol disorder.

What is being tested

• Alert-based computerized decision support (device)

Sponsor: Brigham and Women's Hospital · Participants: 450 · Started: Apr 1, 2025

Contact the study team

• Gregory Piazza, MD, MS · Phone: 6177326984

Official record on ClinicalTrials.gov — NCT06743659

Locations in the U.S.

Conditions

• Hyperlipoproteinemia Type II
• Cholesterol

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.