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Chronic Progressive Multiple Sclerosis clinical trials recruiting in the U.S.
18 studies for Chronic Progressive Multiple Sclerosis are recruiting participants at sites across the United States.
Cities with the most studies
- St. Louis, MO4 studies
- Memphis, TN4 studies
- Chicago, IL4 studies
- Kansas City, KS3 studies
- Burbank, CA3 studies
- Orlando, FL3 studies
- Columbus, OH3 studies
- Greenville, SC3 studies
- Tampa, FL3 studies
By state
- Arizona3 studies
- California10 studies
- Florida3 studies
- Georgia3 studies
- Illinois5 studies
- Kansas4 studies
- Michigan4 studies
- Missouri4 studies
- North Carolina3 studies
- Ohio6 studies
- South Carolina3 studies
- Tennessee4 studies
- Texas4 studies
- Washington3 studies
Recently updated studies
A Phase 2a Study of SUN-627 in Participants With Non-Active Secondary Progressive and Primary Progressive Multiple Sclerosis (SPMS/PPMS)
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 25, 2026 · NCT07840326A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
RecruitingPhase 3
Ages 18 to 60 · All sexes · Updated Sep 23, 2026 · NCT07299019A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
RecruitingPhase 3
Ages 18 to 60 · All sexes · Updated Sep 22, 2026 · NCT07067463Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT07477639Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
RecruitingPhase 3
Ages 18 to 55 · All sexes · Updated Sep 16, 2026 · NCT04047628A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 8, 2026 · NCT07609719Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)
RecruitingPhase 1/2
Ages 18 to 120 · All sexes · Updated Aug 27, 2026 · NCT03109288A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Jul 29, 2026 · NCT07225504Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
RecruitingPhase 1/2
Ages 18 to 55 · All sexes · Updated Jul 2, 2026 · NCT05359653Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
RecruitingPhase 1
Ages 18 to 60 · All sexes · Updated Mar 23, 2026 · NCT07139743Intermittent Hypoxia in Persons With Multiple Sclerosis
Recruiting
Ages 18 to 75 · All sexes · Updated Mar 20, 2026 · NCT06276634A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Feb 27, 2026 · NCT06138132Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS
Recruiting
Ages 18 to 75 · All sexes · Updated Feb 23, 2026 · NCT06390930Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients
Recruiting
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT07392879Home Based Functional Balance Intervention for Multiple Sclerosis
Recruiting
Ages 40 to 90 · All sexes · Updated Jan 21, 2026 · NCT07355387"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT07222618Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
Recruiting
Ages 22 to 75 · All sexes · Updated Sep 24, 2025 · NCT05964829MS-ResearchBiomarkerS
RecruitingObservational studyHealthy volunteers welcomeMentions payment for participants
Ages 18 and older · All sexes · Updated Feb 6, 2024 · NCT05204459From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.