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"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS

RecruitingObservational study

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Any patient with MS who is above the age of 18 yrs. Participants who are unable to consent for themselves must have a surrogate decision maker or LAR.
* Age \> 18 yrs, EDSS - \<6.5, own a video recording device (smartphone, tablet, camera etc).

Exclusion Criteria:

* Patient unwilling to participate in the study. Participants unable to consent for themselves who do not have a surrogate decision maker or LAR.

About the study

The goal of this observational study is to validate a novel, cost-effective method for real-world assessment using patient-acquired "selfie" videos in people with multiple sclerosis. The investigators aim to prove the feasibility and validity of monitoring walking changes remotely through a truly patient-centered, low-burden, low-cost approach. The main question this study aims to answer is: do remotely collected walking and speech videos from a mobile phone match the information investigators can gather from an in person visit?

Participants will collect 5 "selfie" videos at baseline, 3 months, 6 months and 12 months (about 15 minutes every 3 months). They will also come in person at baseline, 6 months, and 12 months for in person data collection (about 1 hour per in person visit).

Sponsor: University of California, San Francisco · Participants: 300 · Started: Oct 1, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07222618

Locations in the U.S.

CaliforniaUniversity of California, San Francisco, San Francisco

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.