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COPD clinical trials in North Carolina

24 studies for COPD are looking for participants at sites in North Carolina.

Cities in North Carolina

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

  • Wake Forest School of Medicine, Salem
Recruiting
Ages 40 to 80 · All sexes · Updated Nov 5, 2026 · NCT07051707

WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

  • Wake Forest Baptist Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07558265

To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

  • Eximia Research, Raleigh
  • Carolina Research Center, Inc., Shelby
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Oct 28, 2026 · NCT07684820

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

  • Research Site, New Bern
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Oct 23, 2026 · NCT07082738

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

  • East Carolina University- Site Number : 8400102, Greenville
  • All-Trials Clinical Research- Site Number : 8400008, Winston-Salem
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 23, 2026 · NCT07190222

A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)

  • WB Contracted Clinical Research Site, Charlotte
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Oct 23, 2026 · NCT07646587

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

  • Salem Chest Specialists, Winston-Salem
  • Southeastern Research Center, Winston-Salem
RecruitingPhase 2/3
Ages 35 to 80 · All sexes · Updated Oct 22, 2026 · NCT07363694

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

  • American Health Research - Charlotte- Site Number : 8400013, Charlotte
  • Atrium Health Wake Forest Baptist Pulmonary, Sleep And Allergy- Site Number : 8400004, Winston-Salem
RecruitingPhase 4
Ages 40 to 85 · All sexes · Updated Oct 20, 2026 · NCT07053423

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

  • Duke Asthma, Allergy and Airway Center- Site Number : 8400047, Durham
  • Advanced Respiratory and Sleep Medicine - Hickory- Site Number : 8400013, Hickory
  • Science 37, Llc- Site Number : 8400154, Morrisville
  • and 1 more
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 19, 2026 · NCT07190209

STRIVE Post-Market Registry Study

  • Duke University Medical Center, Durham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT04302272

The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry

  • Duke, Durham
RecruitingObservational study
Ages 40 and older · All sexes · Updated Oct 15, 2026 · NCT07612878

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

  • Research Site, Charlotte
  • Research Site, Concord
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 9, 2026 · NCT06878261

Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

  • GSK Investigational Site, Shelby
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 5, 2026 · NCT06961214

Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation

  • GSK Investigational Site, Winston-Salem
  • GSK Investigational Site, Winston-Salem
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 5, 2026 · NCT06959095

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

  • Research Site, Greensboro
  • Research Site, Greenville
  • Research Site, Huntersville
  • and 3 more
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Oct 2, 2026 · NCT06283966

Nebulizer Versus Handheld Maintenance Therapy for Patients With COPD

  • Southeastern Research Center, Winston-Salem
RecruitingPhase 4
Ages 60 and older · All sexes · Updated Sep 14, 2026 · NCT07816835

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

  • Research Site, High Point
  • Research Site, Kings Mountain
  • Research Site, New Bern
  • and 1 more
RecruitingPhase 3
Ages 40 to 80 · All sexes · Updated Sep 3, 2026 · NCT06883305

Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia

  • Duke Asthma Allergy and Airway Center, Durham
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Aug 27, 2026 · NCT07037836

Photon-counting CT in Chest Imaging

  • Duke University Hospital, Durham
Recruiting
All ages · All sexes · Updated Aug 26, 2026 · NCT07031336

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

  • GSK Investigational Site, Winston-Salem
RecruitingPhase 3
Ages 40 to 75 · All sexes · Updated Jul 28, 2026 · NCT07177339

SPIROMICS Study of Early COPD Progression (SOURCE)

  • Wake Forest, Winston-Salem
RecruitingObservational studyHealthy volunteers welcome
Ages 30 to 55 · All sexes · Updated Jun 3, 2026 · NCT05033990

Pulmonary Hypertension SOLAR

  • Duke University Medical Center, Durham
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 24, 2026 · NCT04778046

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

  • Wakemed, Raleigh
RecruitingObservational study
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.