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Critical Illness clinical trials recruiting in the U.S.
45 studies for Critical Illness are recruiting participants at sites across the United States.
Cities with the most studies
- Durham, NC9 studies
- New York City, NY5 studies
- Baltimore, MD4 studies
- Nashville, TN4 studies
- Boston, MA4 studies
- Portland, OR3 studies
- Winston-Salem, NC3 studies
- Gainesville, FL3 studies
- Houston, TX3 studies
- Philadelphia, PA3 studies
- Cincinnati, OH3 studies
- St. Louis, MO3 studies
- Chicago, IL3 studies
- Mountain View, CA3 studies
- Buffalo, NY3 studies
- Rochester, MN3 studies
- Seattle, WA3 studies
- Little Rock, AR3 studies
- Birmingham, AL3 studies
- Rochester, NY3 studies
- New Haven, CT3 studies
- Columbus, OH3 studies
By state
- Alabama3 studies
- Arkansas3 studies
- California7 studies
- Colorado4 studies
- Connecticut4 studies
- Florida10 studies
- Illinois4 studies
- Kentucky3 studies
- Maryland5 studies
- Massachusetts5 studies
- Minnesota5 studies
- Missouri4 studies
- New York7 studies
- North Carolina11 studies
- Ohio6 studies
- Oregon3 studies
- Pennsylvania6 studies
- South Carolina3 studies
- Tennessee5 studies
- Texas7 studies
- Washington3 studies
- Wisconsin3 studies
Recently updated studies
Behavioral Economic & Staffing Strategies in the ICU
Recruiting
Ages 19 and older · All sexes · Updated Sep 29, 2026 · NCT06184945VoiceLove: An App-Based COMMunication Tool Designed to Address DeliriUm and Improve Family ENgagement and PatIent/Family SatisfaCtion in CriticAlly Ill PaTiEnts (COMMUNICATE)
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06923462Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients
RecruitingPhase 2
Ages 18 to 99 · All sexes · Updated Sep 2, 2026 · NCT07639359Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children
RecruitingObservational study
1 Day – 17 Years · All sexes · Updated Aug 27, 2026 · NCT07613918Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
Recruiting
Up to age 18 · All sexes · Updated Aug 24, 2026 · NCT04989790Exogenous Ketone Supplementation in ICU Delirium
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07364162Azithromycin for Critical Asthma - Pediatrics
RecruitingPhase 2/3
Ages 3 to 17 · All sexes · Updated Aug 11, 2026 · NCT06223828COMPARE-VENT Feasibility Pilot Study
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07656259Improving Needs Among Older Adults
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06588556PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia
RecruitingPhase 1/2
7 Days – 28 Days · All sexes · Updated Jul 14, 2026 · NCT07101640MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients
Recruiting
Ages 18 to 85 · All sexes · Updated Jul 10, 2026 · NCT07362862The Effects of Endotracheal Suctioning on Pain and Serum Markers
Recruiting
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06692400Digital and Plasma Biomarkers in Delirium
RecruitingObservational study
Ages 65 and older · All sexes · Updated Jul 9, 2026 · NCT07694206Pervasive Sensing and AI in Intelligent ICU
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT05127265Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06066502Muscle Recovery After Critical Illness
RecruitingObservational study
Ages 18 and older · Men · Updated Jun 26, 2026 · NCT05537298Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06341972Evaluating the Unmet Needs of Older Adults to Promote Functional Recovery After a Critical Illness
RecruitingObservational study
Ages 65 and older · All sexes · Updated Jun 17, 2026 · NCT06006000Preoperative Fasting vs. Not Fasting in Critically Ill Patients
Recruiting
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06751043Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies
RecruitingPhase 2/3
Up to age 17 · All sexes · Updated Jun 8, 2026 · NCT04924322Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery
Recruiting
Ages 45 and older · All sexes · Updated Jun 3, 2026 · NCT06521086REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19
Recruiting
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT05218083NIBP Validation Study
RecruitingObservational study
All ages · All sexes · Updated May 26, 2026 · NCT05673408iNO300 Therapy in Critically Ill Patients With Pneumonia
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06950294Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
Recruiting
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT05551325From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.