Dementia clinical trials in California
29 studies for Dementia are looking for participants at sites in California.
Cities in California
A Study of LY3439539 in Participants With Alzheimer's Disease
- Irvine Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- Inglewood Clinical, Los Angeles
- and 1 more
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Sep 24, 2026 · NCT07598370A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Fullerton Neurology and Headache Center, Fullerton
- Irvine Clinical Research, Irvine
- Inglewood Clinical, Los Angeles
- and 1 more
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type
- Inland Psychiatric Medical Group, Chino
RecruitingPhase 2
All ages · All sexes · Updated Sep 16, 2026 · NCT06052254Alzheimer's Tau Platform: Master Protocol
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 50 to 80 · All sexes · Updated Sep 8, 2026 · NCT06957418Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Fresno VA Medical Center, Fresno
- Long Beach VA Medical Center, Long Beach
- Cedars-Sinai Medical Center, Los Angeles
- and 3 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
- Clinical Site, Anaheim
- Clinical Site, Long Beach
- Clinical Site, Murrieta
- and 2 more
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Aug 27, 2026 · NCT06887192Enhancing Attention and Wellbeing Using Digital Therapeutics
- University of California San Francisco, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 99 · All sexes · Updated Aug 24, 2026 · NCT06397469A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
- Healthy Brain Clinic, Long Beach
- Anderson Clinical Research, Redlands
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital Testing Platform Across the Lifespan
- The Neurology Center of Southern California, Carlsbad
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Aug 17, 2026 · NCT07763392A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
- University of California San Diego Medical Center, La Jolla
- University of Southern Califonria, Los Angeles
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
- University of California San Diego Medical Center, La Jolla
- University of Southern Califonria, Los Angeles
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
- Care Access - Huntington Beach, Huntington Beach
- Irvine Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- and 6 more
RecruitingPhase 3
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
- Inland Psychiatric Medical Group., Chino
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Jun 30, 2026 · NCT06947941A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
- Irvine Center for Clinical Research, Irvine
- University of California San Diego, La Jolla
- University of California at Los Angeles, Los Angeles
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516A Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers
- University of California San Diego, La Jolla
- University of California Los Angeles, Los Angeles
- Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05452031The INSPIRE -Faith Study: Intervention Strategies for Preserving Intellectual Resilience and Engagement
- Crenshaw Christian Center, Los Angeles
RecruitingHealthy volunteers welcome
Ages 55 to 85 · All sexes · Updated May 28, 2026 · NCT06741865Preventing Medication Mismanagement in People Living With Dementia
- HiDO Technologies, Folsom
Recruiting
Ages 65 and older · All sexes · Updated May 22, 2026 · NCT07600684Trial-Ready Cohort-Down Syndrome (TRC-DS)
- University of California, Irvine School of Medicine, Co-Enrolling through ABC-DS Only, Orange
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109New Approach to Objectively Measure Social Engagement in Older Adults With Hearing Loss
- Los Angeles General Medical Center, Los Angeles
- University of Southern California, Los Angeles
RecruitingObservational studyHealthy volunteers welcome
Ages 60 and older · All sexes · Updated May 11, 2026 · NCT06781749Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.
- University of Southern California, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06418971Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study
- University of California, Los Angeles
- University of California, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
- University of California San Francisco, San Francisco
Recruiting
Ages 55 to 89 · All sexes · Updated Dec 11, 2025 · NCT04171323Dementia and Diabetes Prevention Program
- University of California, Davis Alzheimer's Disease Center, Walnut Creek
Recruiting
Ages 60 and older · All sexes · Updated Dec 5, 2025 · NCT04141878Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study
- CSMC, Los Angeles
Recruiting
Ages 55 to 89 · All sexes · Updated Nov 19, 2025 · NCT07224607TabCAT Brain Health Assessment in Primary Care
- Kaiser Permanente Southern California Department of Research & Evaluation, Pasadena
Recruiting
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT06090578Alzheimer Prevention Trials (APT) Webstudy
- Https://Www.Aptwebstudy.Org, San Diego
RecruitingObservational studyHealthy volunteers welcome
Ages 50 to 85 · All sexes · Updated Jul 16, 2025 · NCT03638583First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
- China Basin, UCSF, San Francisco
RecruitingPhase 1/2Healthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Apr 17, 2025 · NCT05374278Phase I Human Analytics (HALO) Study
- Desert Medical Imaging, Indian Wells
RecruitingObservational study
Ages 45 to 90 · Men · Updated Oct 14, 2022 · NCT05423860Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
- Southern California Hospital at Culver City / Southern California Hospital at Hollywood / Multiple US-based Sub-Investigator Sites, Culver City
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 29, 2022 · NCT04684602From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.