Home › Mild Cognitive Impairment › NCT06397469

Enhancing Attention and Wellbeing Using Digital Therapeutics

Optimizing a Closed-loop Digital Meditation Intervention for Remediating Cognitive Decline and Reducing Stress in Older Adults

Who can join

Ages 60 to 99 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* 60+ years old (adult)
* English language fluency
* owning a smartphone or tablet

Exclusion Criteria:

* Under 60 years old (minor)

About the study

The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment effects (i.e., cognitive decline, AD polygenic hazard score, cardiovascular risk, and race/ethnicity). This knowledge gained from his high-impact study with transform the field of cognitive interventions, paving the way for a precision medicine model for cognitive enhancing interventions that improve quality of life for older adults and individuals with cognitive deficits at risk of developing dementia.

What is being tested

• MediTrain (device)
• Worder (device)

Sponsor: University of California, San Francisco · Participants: 4,000 · Started: Apr 1, 2024

Contact the study team

• David Ziegler, PhD · Phone: 4154762164
• Monique de Villa, MS, MPH · Phone: 209-233-3878

Official record on ClinicalTrials.gov — NCT06397469

Locations in the U.S.

Conditions

• Mild Cognitive Impairment
• Dementia

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.