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Diffuse Large B-Cell Lymphoma clinical trials in Texas

29 studies for Diffuse Large B-Cell Lymphoma are looking for participants at sites in Texas.

Cities in Texas

Loncastuximab and Roflumilast Added to R-CHOP (Lo-(Rituximab and Roflumilast) RR-CHOP) for Naïve High-Risk Diffuse Large B-cell Lymphoma (DLBCL)

  • University Hospital System, San Antonio
  • University of Texas Health Science Center San Antonio at the Cancer Therapy and Research Center, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06977711

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

  • Md Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05006716

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

  • Texas Oncology - West Texas ( Site 8008), Amarillo
  • Texas Oncology - Central/South Texas ( Site 8006), Austin
  • UT Southwestern Medical Center ( Site 0190), Dallas
  • and 2 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06890884

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

  • Texas Oncology - DFW ( Site 8000), Dallas
  • Houston Methodist Cancer Center ( Site 0154), Houston
  • Joe Arrington Cancer Research and Treatment Center ( Site 0183), Lubbock
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06717347

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

  • Texas Oncology - DFW (Sammons CC), Dallas
  • Baylor College of Medicine, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07226843

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

  • University of Texas Southwestern, Dallas
  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07101328

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

  • University of Texas MD Anderson Cancer Center ( Site 1007), Houston
RecruitingPhase 1/2
6 Months – 25 Years · All sexes · Updated Sep 17, 2026 · NCT06395103

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

  • Md Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07195916

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

  • Baylor Scott & White Health, Temple
  • Texas Oncology - Gulf Coast, The Woodlands
  • Texas Oncology- Northeast Texas, Tyler
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06806033

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

  • Texas Oncology - Central South, Austin
  • Texas Oncology - Dallas Fort Worth, Dallas
  • MD Anderson Cancer Center, Houston
  • and 2 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT06500273

Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07284433

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

  • Baylor University Medical Center, Dallas
  • Texas Transplant Institute, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT05826535

Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL)

  • Natera, Inc., Austin
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07750886

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

  • University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 13 to 90 · All sexes · Updated Aug 6, 2026 · NCT06533579

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

  • UT Southwestern Medical Center, Dallas
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06116110

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

  • St. David's South Austin Medical Center, Austin
  • University of Texas Southwestern Medical Center, Fort Worth
  • MD Anderson Cancer Center, Houston
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07188558

A Study of APG-3288 in Relapsed/Refractory Blood Cancers

  • The University of TX MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07424833

DALY II USA/ MB-CART2019.1 for DLBCL

  • UT Southwestern Medical Center, Dallas
  • The University of Texas MD Anderson Cancer Center, Houston
  • Texas Transplant Institute, San Antonio
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT04792489

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

  • University of Texas Southwestern Medical Center, Dallas
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05852717

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

  • Texas Children's Hospital, Houston
RecruitingObservational study
Ages 0 to 38 · All sexes · Updated Jun 4, 2026 · NCT06131801

IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

  • University of Texas Southwestern Medical Center, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06768905

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

  • University of Texas(UT) Southwestern-Children's Medical Center, Dallas
RecruitingPhase 1/2
Ages 12 to 95 · All sexes · Updated Apr 15, 2026 · NCT04329728

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

  • NEXT Oncology, Austin, TX 78758
  • NEXT Oncology, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT06451497

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04830137

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • Ben Taub General Hospital, Houston
  • University of Texas Health Science Center at San Antonio, San Antonio
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 20, 2025 · NCT05890352

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

  • University of Texas Southwestern Medical Center, Dallas
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05780034

A Study of NX-1607 in Adults With Advanced Malignancies

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

  • UT Southwestern Medical Center, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 4, 2022 · NCT04502394

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.