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Down Syndrome clinical trials in Tennessee

8 studies for Down Syndrome are looking for participants at sites in Tennessee.

Cities in Tennessee

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

  • East Tennessee Childrens Hospital, Knoxville
  • The Children's Hospital at TriStar Centennial, Nashville
  • Vanderbilt University/Ingram Cancer Center, Nashville
RecruitingPhase 2
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

  • East Tennessee Childrens Hospital, Knoxville
  • Saint Jude Children's Research Hospital, Memphis
  • Vanderbilt University/Ingram Cancer Center, Nashville
RecruitingObservational study
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

  • Neurology Clinical, P.C., Cordova
RecruitingPhase 1/2
Ages 35 to 85 · All sexes · Updated Jul 10, 2026 · NCT05462106

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

  • Vanderbilt University Medical Center Clinical Research Center, Nashville
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Jun 22, 2026 · NCT05231798

Collaboration for Down Syndrome Progress (CDP)

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579

Drumming Lessons' Influence on Children With Down Syndrome

  • Vanderbilt University, Nashville
Recruiting
Ages 7 to 15 · All sexes · Updated May 19, 2026 · NCT07156318

Trial-Ready Cohort-Down Syndrome (TRC-DS)

  • Vanderbilt University Medical Center Center for Cognitive Medicine, Nashville
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

  • Woolfson Eye Institute, Chattanooga
  • Woolfson Eye Institute, Johnson City
  • Woolfson Eye Institute, Knoxville
RecruitingPhase 3
Ages 8 and older · All sexes · Updated Feb 2, 2026 · NCT07135167

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.