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Endometrial Cancer clinical trials in Illinois

35 studies for Endometrial Cancer are looking for participants at sites in Illinois.

Cities in Illinois

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

  • Carle at The Riverfront, Danville
  • Carle Physician Group-Effingham, Effingham
  • Carle Physician Group-Mattoon/Charleston, Mattoon
  • and 3 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT05112601

Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

  • University of Illinois at Chicago (UIC), Chicago
  • University of Chicago, Chicago
RecruitingPhase 1/2
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT04683653

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

  • University of Chicago Comprehensive Cancer Center, Chicago
RecruitingPhase 1
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT05950464

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

  • Advocate Good Shepherd Hospital, Barrington
  • Illinois CancerCare-Bloomington, Bloomington
  • Illinois CancerCare-Canton, Canton
  • and 58 more
RecruitingPhase 2
All ages · All sexes · Updated Nov 12, 2026 · NCT05564377

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

  • Northwestern University, Chicago
  • Northwestern Medicine Orland Park, Orland Park
  • Northwestern Medicine Cancer Center Warrenville, Warrenville
RecruitingPhase 2
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT05640999

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

  • OSF Saint Francis Medical Center, Peoria
  • Carle Cancer Institute, Urbana
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 10, 2026 · NCT06340568

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

  • Northwestern University, Chicago
  • Rush MD Anderson Cancer Center, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
  • and 26 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 6, 2026 · NCT07198074

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

  • University of Chicago, Chicago
RecruitingObservational study
Ages 18 and older · Women · Updated Nov 5, 2026 · NCT05051722

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

  • Endeavor Health NorthShore, Evanston
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 3, 2026 · NCT07166094

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • City of Hope, Chicago, Zion
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07109726

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • Orchard Healthcare Research Inc, Skokie
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06330064

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • University of Illinois Cancer Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478

Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy

  • Northwestern Memorial Hospital, Chicago
Recruiting
Ages 18 and older · Women · Updated Oct 15, 2026 · NCT05990426

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

  • University of Illinois Cancer Center, Chicago
  • University of Chicago Medicine, Chicago
  • City of Hope - Chicago, Zion
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06293898

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

  • University of Chicago Medical Center, Chicago
RecruitingPhase 1
Ages 15 and older · All sexes · Updated Oct 9, 2026 · NCT06276491

A Study of PHST001 in Advanced Solid Tumors

  • University of Chicago Medical Center, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886

DESTINY-PANTUMOUR04

  • Research Site, Decatur
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
  • University of Chicago Medical Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT04590326

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Northwestern University Feinberg School of Medicine, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • Lurie Children's Hospital-Chicago, Chicago
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

  • Northwestern Medicine, Chicago
  • University of Illinois Cancer Center, Chicago
  • University of Chicago Medicine, Chicago
  • and 1 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Aug 21, 2026 · NCT05548296

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

  • University of Chicago Medical Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

  • St. Francis Medical Center (OSF Healthcare), Peoria
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07470853

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

  • St. Francis Medical Center (OSF Healthcare), Peoria
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

  • Research Site, Chicago
  • Research Site, Peoria
  • Research Site, Urbana
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

  • Northwestern University, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Integrated Cancer Repository for Cancer Research

  • Rush-Copley Cancer Care Center, Aurora
  • Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

  • University of Chicago Medical Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

  • Kellogg Cancer Center, Evanston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

  • Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 80 · Women · Updated Feb 28, 2025 · NCT00005095

Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer

  • Dr. Sudarshan K. Sharma, Ltd., Hinsdale
RecruitingPhase 2/3
Ages 18 and older · Women · Updated May 2, 2024 · NCT05797831

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.