Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

DISEASE CHARACTERISTICS:

* Meets one of the following criteria:

  * Considered to be at increased risk for developing ovarian cancer, as defined by one of the following:

    * Has at least one first-degree relative (mother, sister, or daughter) with ovarian, primary peritoneal, or fallopian tube cancer
    * Has at least two first or second degree relatives diagnosed before age 50 with either ovarian, primary peritoneal, fallopian tube, and/or pancreatic cancer who have tested positive for hereditary cancer syndrome that includes an increased risk of gynecologic cancer (e.g., BRCA1/2 or Lynch Syndrome)or have increased risk as deemed by a certified genetic counselor
    * A personal or family history of a hereditary cancer syndrome that includes an increased risk of gynecologic cancer
    * Increased risk as deemed by a certified genetic counselor
  * Undergoing surgery for a gynecologic condition, including any of the following:

    * Diagnosis of a reproductive cancer
    * Benign gynecological condition (e.g., uterine leiomyomata, endometriosis, pelvic inflammatory disease, or follicular or corpus luteum ovarian cysts)
    * Highly suspicious adnexal mass
    * Risk-reducing prophylactic oophorectomy

PATIENT CHARACTERISTICS:

Age

* Between the ages of 18 and 80