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Esophageal Cancer clinical trials in Florida

32 studies for Esophageal Cancer are looking for participants at sites in Florida.

Cities in Florida

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
  • Morton Plant Hospital, Clearwater
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Holy Cross Hospital, Fort Lauderdale
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07283939

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Holy Cross Hospital (site 213), Fort Lauderdale
  • Memorial Cancer Institute at Memorial Healthcare Systems (site 132), Pembroke Pines
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT03556228

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07213791

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07114601

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

  • Florida Cancer Specialists & Research Institute - Fort Myers Cancer Center - Gladiolus, Fort Myers
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06760819

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

  • Florida Cancer Specialists & Research Institute - Sarasota Cattlemen, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07578571

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

  • University of Florida, Gainesville
  • Sarah Cannon Research Institute (Lake Nona), Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT03526835

Lead-212 PSV359 Therapy for Patients With Solid Tumors

  • University of Miami, Miami
  • Biogenix, Miami
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Oct 28, 2026 · NCT06710756

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478

Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic

  • SCRI at Florida Cancer Specialists, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07807345

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

  • Impression Imaging, Coral Springs
  • Mayo Clinic Jacksonville, Jacksonville
  • Moffit Cancer Center, Tampa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT07217704

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

  • Research Site, Jacksonville
  • Research Site, Jacksonville
  • Research Site, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07431281

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

  • University of Miami, Miami
  • Sarah Cannon Research Institute - Lake Nona Florida, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06293898

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06265285

DESTINY-PANTUMOUR04

  • Research Site, Coral Springs
  • Research Site, St. Petersburg
  • Research Site, West Palm Beach
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

  • MDR Core Network, Boynton Beach
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

Pan-tumor MRD Study

  • Oncology & Hematology Associates of West Broward, Coral Springs
  • Mid Florida Cancer Centers, Orange City
  • Comprehensive Hematology Oncology (CHO), St. Petersburg
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Florida Cancer Specialists, Sarasota
  • Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Sylvester Comprehensive Cancer Center, Miami
  • Sara Cannon Research Institute Lake Nona, Orlando
  • Hematology - Oncology Associates of the Treasure Coast, Port Saint Lucie
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Memorial Healthcare System, Hollywood
  • The Oncology Institute of Hope & Innovation, Lakeland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

  • SCRI FCS Sarasota, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168

Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma

  • Cleveland Clinic Florida, Weston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07222657

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

  • AdventHealth Celebration, Celebration
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

  • American Oncology Partners, PA. a Florida professional service corporation, d/b/a Vista Oncology, Fort Myers
  • Florida Cancer Specialists & Research Institute, LLC, Fort Myers
  • Memorial Cancer Institute, Hollywood
  • and 4 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Integrated Cancer Repository for Cancer Research

  • Florida Hospital Memorial Medical Center, Daytona Beach
  • Florida Hospital DeLand, DeLand
  • Florida Hospital FISH, Orange City
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

  • Mayo Clinic in Florida, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06349642

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

  • Florida Cancer Specialists & Research Institute, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 12, 2026 · NCT07181473

Exercise Prehabilitation for Locoregional Esophageal Cancer

  • Moffitt Cancer Center, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Dec 4, 2025 · NCT06430346

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Jacksonville
  • Massive Bio SYNERGY-AI site, Miami
  • Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

  • Moffitt Cancer Center, Tampa
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Feb 28, 2025 · NCT02634645

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.