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Esophageal Squamous Cell Carcinoma clinical trials in California
24 studies for Esophageal Squamous Cell Carcinoma are looking for participants at sites in California.
Cities in California
- Los Angeles11 studies
- Baldwin Park8 studies
- Santa Monica6 studies
- Irvine4 studies
- San Francisco3 studies
- Fullerton3 studies
- Orange3 studies
A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)
- UCLA Hematology/Oncology - Santa Monica ( Site 4905), Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05319730A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
- City of Hope National Medical Center, Duarte
- City of Hope at Irvine Lennar, Irvine
- Ronald Reagan UCLA Medical Center, Los Angeles
- and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
- ALX Center 9, La Jolla
- ALX Center 11, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
- City of Hope Cancer Center-Duarte, Duarte
- Providence Medical Foundation, Santa Rosa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
- Kivu Trial Site, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07229313Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
- Precision NextGen Oncology, Beverly Hills
- OPN Healthcare, Inc, Glendale
- University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
- City of Hope, Duarte
- City of Hope, Irvine, Irvine
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
- City of Hope, Duarte
- USC/Norris Comprehensive Cancer Center, Los Angeles
- UCSF Medical center Parnassus, San Francisco
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07217171A Study of IDP-001 in Advanced or Metastatic Solid Tumors
- START Los Angeles, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07602842A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States
- Helios Clinical Research, Cerritos
- Los Angeles Cancer Network, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07554521Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers
- University of California, San Francisco, San Francisco
- John Muir Medical Center-Walnut Creek, Walnut Creek
Recruiting
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT04221893A Study of MGC026 in Participants With Advanced Solid Tumors
- The Angeles Clinic and Research Institute, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
- Providence Medical Foundation, Fullerton
- Univ of California Irvine College of Medicine, Orange
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT06644781A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
- Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
- UC Irvine Health - Chao Family Comprehensive Cancer Center, Orange
- University of California Davis Comprehensive Cancer Center, Sacramento
- and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
- City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer
- City of Hope Nat Medical Ctr, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07224750Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell Carcinoma
- City of Hope Medical Center, Monrovia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07266363A Study of Sigvotatug Vedotin in Advanced Solid Tumors
- Providence Medical Foundation, Anaheim
- Providence Medical Foundation, Fullerton
- Providence St. Jude Medical Center Virginia K Crosson and Infusion Center, Fullerton
- and 7 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors
- Providence Medical Foundation, Fullerton
- USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06747585Study of XB010 in Subjects With Solid Tumors
- City of Hope Orange County Lennar Foundation Cancer Center, Irvine
- UCLA Department of Medicine - Hematology/Oncology, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06545331First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors
- Research Site, Duarte
- Research Site, Orange
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07284186A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
- Research Site 125, Los Angeles
- Research Site 133, Los Angeles
- Research Site 103, Los Angeles
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer
- VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT05563766A Multicenter Cancer Biospecimen Collection Study
- Curebase, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2025 · NCT04510129From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.