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Fatigue clinical trials recruiting in the U.S.
59 studies for Fatigue are recruiting participants at sites across the United States.
Are you tired? Find out about some of the common and uncommon causes of fatigue and how to help yourself.
Cities with the most studies
- Baltimore, MD8 studies
- Houston, TX7 studies
- New York City, NY7 studies
- Charlotte, NC6 studies
- Nashville, TN5 studies
- Birmingham, AL5 studies
- Miami, FL4 studies
- Cincinnati, OH4 studies
- Seattle, WA4 studies
- Pittsburgh, PA3 studies
- Philadelphia, PA3 studies
- League City, TX3 studies
- Charleston, SC3 studies
- Atlanta, GA3 studies
- Peoria, AZ3 studies
- Spokane, WA3 studies
- Boston, MA3 studies
- Reading, PA3 studies
- Los Angeles, CA3 studies
- Columbia, SC3 studies
- Austin, TX3 studies
- Orlando, FL3 studies
- Madison, WI3 studies
- Sugar Land, TX3 studies
- Dallas, TX3 studies
- Macon, GA3 studies
- Boulder, CO3 studies
- Farmington Hills, MI3 studies
- Morgantown, WV3 studies
- San Antonio, TX3 studies
- Chicago, IL3 studies
By state
- Alabama7 studies
- Arizona7 studies
- California6 studies
- Colorado4 studies
- Florida9 studies
- Georgia5 studies
- Illinois6 studies
- Indiana4 studies
- Kansas4 studies
- Louisiana3 studies
- Maryland8 studies
- Massachusetts4 studies
- Michigan9 studies
- Missouri5 studies
- New Jersey3 studies
- New York11 studies
- North Carolina7 studies
- Ohio5 studies
- Oklahoma4 studies
- Pennsylvania6 studies
- South Carolina4 studies
- Tennessee6 studies
- Texas12 studies
- Washington7 studies
- West Virginia3 studies
- Wisconsin5 studies
Recently updated studies
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjรถgren's Disease With High Symptom Burden
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07621809A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06989437Cardiac Output and Fatigue in Friedreich's Ataxia
Recruiting
All ages ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07444333Natural History Study of Mitochondrial Myopathy
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 100 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT05250375Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue
RecruitingPhase 2
Ages 34 to 80 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT05584124A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07500090C-Protein in Fatigue and Aging
RecruitingHealthy volunteers welcome
Ages 18 to 80 ยท All sexes ยท Updated Sep 9, 2026 ยท NCT05926219A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07455383Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD
Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07014111A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 27, 2026 ยท NCT07675135Near-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fatigue Resistance in Young Healthy Adults
RecruitingHealthy volunteers welcome
Ages 18 to 40 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT07654946Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients
Recruiting
Ages 18 and older ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06978127Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients
Recruiting
Ages 6 and older ยท Men ยท Updated Aug 17, 2026 ยท NCT07766980Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of a Tele-exercise Intervention
Recruiting
Ages 18 to 39 ยท All sexes ยท Updated Aug 12, 2026 ยท NCT07186556Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders
Recruiting
Ages 18 to 100 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07180537Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06634381Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 10, 2026 ยท NCT07581080Telephone Support in Advanced Gastrointestinal Cancer
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 6, 2026 ยท NCT06532877Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity
Recruiting
Ages 60 and older ยท All sexes ยท Updated Jun 25, 2026 ยท NCT07554443Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome
Recruiting
Ages 50 to 94 ยท All sexes ยท Updated Jun 23, 2026 ยท NCT05977179Training in Evidence-based Treatments in Psycho-Oncology
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 15, 2026 ยท NCT05674357Solriamfetol for the Treatment of Multiple Sclerosis Fatigue
RecruitingPhase 2
Ages 18 to 60 ยท All sexes ยท Updated Jun 9, 2026 ยท NCT06170970Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 5, 2026 ยท NCT06614309Take the Reins: The Effects of Nutrient Timing on Cancer-related Fatigue
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jun 5, 2026 ยท NCT06482515Active Living After Cancer: Implementation Within Be Well Acres Homes
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 1, 2026 ยท NCT06907706From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.