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Fatigue clinical trials recruiting in the U.S.
62 studies for Fatigue are recruiting participants at sites across the United States.
Are you tired? Find out about some of the common and uncommon causes of fatigue and how to help yourself.
Cities with the most studies
- Baltimore, MD8 studies
- Houston, TX7 studies
- New York City, NY7 studies
- Charlotte, NC6 studies
- Birmingham, AL6 studies
- Nashville, TN5 studies
- Miami, FL4 studies
- Pittsburgh, PA4 studies
- Cincinnati, OH4 studies
- Chicago, IL4 studies
- Boston, MA4 studies
- Seattle, WA3 studies
- Dallas, TX3 studies
- Los Angeles, CA3 studies
- League City, TX3 studies
- Macon, GA3 studies
- Reading, PA3 studies
- Sugar Land, TX3 studies
- Austin, TX3 studies
- Staten Island, NY3 studies
- Boulder, CO3 studies
- Orlando, FL3 studies
- Farmington Hills, MI3 studies
- Columbia, SC3 studies
- Madison, WI3 studies
- San Antonio, TX3 studies
- Atlanta, GA3 studies
- Charleston, SC3 studies
- Philadelphia, PA3 studies
- Morgantown, WV3 studies
- Spokane, WA3 studies
- Peoria, AZ3 studies
By state
- Alabama8 studies
- Arizona7 studies
- California8 studies
- Colorado4 studies
- Florida9 studies
- Georgia5 studies
- Illinois8 studies
- Indiana4 studies
- Kansas4 studies
- Louisiana4 studies
- Maryland8 studies
- Massachusetts5 studies
- Michigan9 studies
- Missouri5 studies
- New Jersey5 studies
- New York12 studies
- North Carolina7 studies
- Ohio5 studies
- Oklahoma4 studies
- Pennsylvania6 studies
- South Carolina4 studies
- Tennessee6 studies
- Texas12 studies
- Washington6 studies
- West Virginia3 studies
- Wisconsin5 studies
Recently updated studies
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 13, 2026 ยท NCT07500090A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 13, 2026 ยท NCT07675135Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus
Recruiting
Ages 12 to 22 ยท All sexes ยท Updated Nov 13, 2026 ยท NCT06232304Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.
Recruiting
Ages 45 to 70 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT07831928Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjรถgren's Disease With High Symptom Burden
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07621809Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers
RecruitingPhase 2/3
Ages 18 and older ยท All sexes ยท Updated Oct 19, 2026 ยท NCT06085716Mind-Body Group Interventions for Psychological Distress in Young Breast Cancer Survivors
Recruiting
Ages 18 to 50 ยท Women ยท Updated Oct 16, 2026 ยท NCT07501637A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
Ages 18 and older ยท All sexes ยท Updated Oct 14, 2026 ยท NCT06989437Characterizing Perceived Physical Fatigability in Nusinersen-treated SMA
RecruitingObservational study
Ages 12 and older ยท All sexes ยท Updated Oct 14, 2026 ยท NCT06955897Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients
RecruitingPhase 2
Ages 6 and older ยท Men ยท Updated Oct 8, 2026 ยท NCT07766980A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Oct 7, 2026 ยท NCT07455383The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis
Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 6, 2026 ยท NCT07504120The Impact of Qualia Vitamin C+ on Individuals With Suboptimal and Adequate Vitamin C Levels
RecruitingHealthy volunteers welcome
Ages 25 to 75 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT07652346Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia
Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07151677Cardiac Output and Fatigue in Friedreich's Ataxia
Recruiting
All ages ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07444333Natural History Study of Mitochondrial Myopathy
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 100 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT05250375Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue
RecruitingPhase 2
Ages 34 to 80 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT05584124C-Protein in Fatigue and Aging
RecruitingHealthy volunteers welcome
Ages 18 to 80 ยท All sexes ยท Updated Sep 9, 2026 ยท NCT05926219Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD
Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07014111Near-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fatigue Resistance in Young Healthy Adults
RecruitingHealthy volunteers welcome
Ages 18 to 40 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT07654946Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients
Recruiting
Ages 18 and older ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06978127Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of a Tele-exercise Intervention
Recruiting
Ages 18 to 39 ยท All sexes ยท Updated Aug 12, 2026 ยท NCT07186556Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders
Recruiting
Ages 18 to 100 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07180537Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06634381Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 10, 2026 ยท NCT07581080From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.