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Frontotemporal Dementia clinical trials recruiting in the U.S.
19 studies for Frontotemporal Dementia are recruiting participants at sites across the United States.
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Recently updated studies
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Sep 17, 2026 · NCT03225144AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980)
RecruitingPhase 1
Ages 65 to 80 · All sexes · Updated Aug 21, 2026 · NCT07158905Using the EHR to Advance Genomic Medicine Across a Diverse Health System
Recruiting
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06377033A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
RecruitingPhase 1/2
Ages 30 to 75 · All sexes · Updated Aug 13, 2026 · NCT06064890ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684Neurologic Stem Cell Treatment Study
Recruiting
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT02795052Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
RecruitingHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jun 10, 2026 · NCT05741853Communication Bridge 3 Study
RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Jun 1, 2026 · NCT06191198Intervention for Communication Quality of Life in Primary Progressive Aphasia
Recruiting
Ages 40 and older · All sexes · Updated Apr 21, 2026 · NCT07219680Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
RecruitingPhase 2Healthy volunteers welcome
Ages 45 and older · All sexes · Updated Mar 9, 2026 · NCT06604520Language in Primary Progressive Aphasia
RecruitingObservational study
All ages · All sexes · Updated Feb 27, 2026 · NCT00537004Retinal Imaging in Neurodegenerative Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners
RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Oct 27, 2025 · NCT06613204Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 18, 2025 · NCT01353430Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
RecruitingObservational study
All ages · All sexes · Updated May 29, 2025 · NCT01793168First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
RecruitingPhase 1/2Healthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Apr 17, 2025 · NCT05374278NYSCF Scientific Discovery Biobank
RecruitingObservational study
30 Days · All sexes · Updated Mar 3, 2025 · NCT06203106Longitudinal Cognitive Assessment by BoCA
RecruitingObservational studyHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Aug 1, 2024 · NCT04114994DC Longitudinal Study on Aging and Specimen Bank
RecruitingObservational studyHealthy volunteers welcome
Ages 45 and older · All sexes · Updated Oct 24, 2019 · NCT03702907From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.