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Gastrointestinal Cancers clinical trials recruiting in the U.S.

70 studies for Gastrointestinal Cancers are recruiting participants at sites across the United States.

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Recently updated studies

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Recruiting
Ages 18 to 99 · All sexes · Updated Nov 12, 2026 · NCT04907643

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07020221

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07283939

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06663319

Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced Gastrointestinal (GI) Cancers

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07539311

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07124351

Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT01313442

Avera Cancer Sequencing and Analytics Protocol (ASAP)

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT05142033

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT07529808

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06582017

EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope

Recruiting
Ages 18 to 100 · All sexes · Updated Oct 20, 2026 · NCT06340620

Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal, Gynecological, Breast, or Lung Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06855524

The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04700527

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07544589

DESTINY-PANTUMOUR04

RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05274048

GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer

RecruitingEarly phase 1
Ages 18 to 99 · All sexes · Updated Sep 18, 2026 · NCT07627191

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.