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Gastrointestinal Cancers clinical trials in California

27 studies for Gastrointestinal Cancers are looking for participants at sites in California.

Cities in California

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • UCSF at Berkeley Outpatient Center, Berkeley
  • Alta Bates Summit Medical Center-Herrick Campus Comprehensive Cancer Center, Berkeley
  • UCSD Medical Center - Encinitas, Encinitas
  • and 21 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

  • GSK Investigational Site, Duarte
  • GSK Investigational Site, La Jolla
  • GSK Investigational Site, Los Angeles
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07218926

DESTINY-PANTUMOUR04

  • Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • UC IRVINE Health, Orange
  • UC Davis Comprehensive Cancer Center, Sacramento
  • Stanford Cancer Institute, Stanford
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

  • UC San Diego Moores Cancer Center, La Jolla
  • Cedars-Sinai Cancer at Cedars-Sinai Medical Center, Los Angeles
  • UCLA Hematology/Oncology- Santa Monica, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

  • Stanford Cancer Center, Palo Alto
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05274048

Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT

  • University of California, San Francisco, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06633224

Personalized Health Self-Management Training for Colorectal Cancer Survivors

  • University of Southern California, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05984589

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
  • Mercy Cancer Center - Carmichael, Carmichael
  • Mercy San Juan Medical Center, Carmichael
  • and 8 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • University of Southern California, Los Angeles
  • Cedars-Sanai Medical Center - Samuel Oschin Comprehensive Cancer, Los Angeles
  • Cedars-Sanai Medical Center, Los Angeles
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

  • City of Hope, Duarte
  • Hoag Memorial Hospital Presbyterian, Newport Beach
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07544589

Understanding New Cachexia Subtypes Through Observational Epidemiological Research

  • Kaiser Permanente Northern California, Pleasanton
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07776353

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

  • University of California, San Francisco, San Francisco
  • John Muir Medical Center-Walnut Creek, Walnut Creek
Recruiting
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT04221893

A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)

  • GSK Investigational Site, Los Alamitos
  • GSK Investigational Site, Los Angeles
  • GSK Investigational Site, Santa Monica
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06885034

A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07337525

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

  • City of Hope Nat Medical Ctr, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07224750

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

  • University of California, Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

  • St Joseph Heritage Healthcare, Santa Rosa
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

  • UC Irvine/Chao Family Comprehensive Cancer Center, Orange
  • UCLA, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Clinical Outcomes of the Endoscopic Resection of Premalignant and Malignant Gastrointestinal Lesions

  • Interventional Endoscopy Services, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT01750619

PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis

  • Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT06511037

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 99 · All sexes · Updated Feb 20, 2026 · NCT04907643

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 15, 2025 · NCT07124351

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

  • City Of Hope, Duarte
  • Stanford Cancer Center, Palo Alto
RecruitingObservational study
All ages · All sexes · Updated Aug 15, 2025 · NCT05406167

Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models

  • City of Hope, Duarte
Recruiting
Ages 18 and older · All sexes · Updated Sep 8, 2023 · NCT06002425

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.