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Glioblastoma clinical trials in Illinois

17 studies for Glioblastoma are looking for participants at sites in Illinois.

Cities in Illinois

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

  • Northwestern Univerity, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05303467

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

  • University of Chicago Comprehensive Cancer Center, Chicago
  • University of Chicago Medicine-Orland Park, Orland Park
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05432804

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

  • Northwestern University, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05902169

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

  • Alton Memorial Hospital, Alton
  • Decatur Memorial Hospital, Decatur
  • Northwestern Medicine Cancer Center Kishwaukee, DeKalb
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07452458

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

  • Northwestern University, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06410248

Targeted Pediatric High-Grade Glioma Therapy

  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingObservational study
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

  • Northwestern University, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06860594

Study of Olutasidenib and Temozolomide in HGG

  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingPhase 2
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

  • University of Chicago, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

  • Northwestern University, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT05864534

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

  • Northwestern Medicine, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07464925

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

  • Northwestern University, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05879250

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingEarly phase 1Healthy volunteers welcome
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingPhase 2
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

  • Northwestern Memorial Hospital, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.