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Hairy Cell Leukemia clinical trials recruiting in the U.S.

10 studies for Hairy Cell Leukemia are recruiting participants at sites across the United States.

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Recently updated studies

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT01087333

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04322383

Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04815356

A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06561360

AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06340737

Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients With Hairy Cell Leukemia

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06965114

Registry of Older Patients With Cancer

RecruitingObservational study
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825

Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT00412594

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT04775745

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 27, 2025 · NCT01137643

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.