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Hairy Cell Leukemia clinical trials recruiting in the U.S.
10 studies for Hairy Cell Leukemia are recruiting participants at sites across the United States.
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Recently updated studies
Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT01087333Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04322383Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04815356A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06561360AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06340737Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients With Hairy Cell Leukemia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06965114Registry of Older Patients With Cancer
RecruitingObservational study
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT00412594Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT04775745Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 27, 2025 · NCT01137643From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.