Home › Hairy Cell Leukemia › NCT01087333
Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
A Study of Hairy Cell and Other Leukemias With a Focus on Recombinant Immunotoxins for Cancer Treatment
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
* INCLUSION CRITERIA: All participants * 18 years of age and older * Desire of the individual to submit data and samples for research * Ability to understand and the willingness to sign a written informed consent document. Individuals with cancer -Participants may have a diagnosis of hematologic malignancy or solid tumor. These participants would not be excluded if they were in long-term complete remission. Normal donors (Individuals without cancer) -Individuals must not have a current or prior diagnosis of a hematologic malignancy or solid tumor. EXCLUSION CRITERIA: All participants -Known pregnancy at enrollment. NOTE: A pregnancy test will be required in individuals on study prior to any procedure done for research purposes that is greater than minimal risk.
About the study
Background:
\- Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients and healthy volunteers. The investigators are particularly interested in samples from individuals who have diseases that can be treated with a new type of drug called immunotoxin, in which an antibody carrying a toxin binds to a cancer cell and allows the toxin to kill the cell.
Objectives:
\- To collect a variety of clinical samples, including blood, urine, lymph samples, and other tissues, in order to study the samples and develop new treatments for leukemia.
Eligibility:
\- Individuals 18 years of age and older who have been diagnosed with leukemia or other kinds of blood and lymphatic system cancers, or who are healthy volunteers.
Design:
* Individuals who have leukemia will be asked to provide blood, bone marrow, urine, and tumor tissue samples as requested by the researchers. Healthy volunteers will provide only blood and urine samples. * No treatment will be given as part of this protocol.
Sponsor: National Cancer Institute (NCI) · Participants: 1,263 · Started: Mar 2, 2010
Contact the study team
- Julie C Feurtado, R.N. · Phone: (301) 480-6186
- Robert J Kreitman, M.D. · Phone: (301) 648-7375
Official record on ClinicalTrials.gov — NCT01087333
Locations in the U.S.
| Maryland | National Institutes of Health Clinical Center, Bethesda |
Conditions
- Hairy Cell Leukemia
- Chronic Lymphocytic Leukemia
- Non-Hodgkin Lymphoma
- Cutaneous T-Cell Lymphoma
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.