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Head and Neck Cancer clinical trials in Florida
25 studies for Head and Neck Cancer are looking for participants at sites in Florida.
Cities in Florida
A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer
- Florida Cancer Specialists (from Sarah Canon research Institute), Orlando
- Tampa General Hospital, Tampa
- Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06319963Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
- Clermont Oncology Center, Clermont
- Mid Florida Hematology and Oncology Center, Orange City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT04198766VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
- Holy Cross Hospital (site 213), Fort Lauderdale
- Memorial Cancer Institute at Memorial Healthcare Systems (site 132), Pembroke Pines
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT03556228FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
- Mayo Clinic Florida (Site #0148), Jacksonville
- Cancer Care Centers of Brevard (Site #0136), Palm Bay
- Moffit Cancer Center (Site #0105), Tampa
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06788990Ordastobart (INBRX-106) Add-on to Pembrolizumab in 1L HPV+ PD-L1+ R/M OPSCC (HexAgon-HN)
- The Oncology Institute of Hope & Innovation, Miami
- Mid Florida Hematology and Oncology Center, Orange City
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT06295731Lead-212 PSV359 Therapy for Patients With Solid Tumors
- University of Miami, Miami
- Biogenix, Miami
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Oct 28, 2026 · NCT06710756A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
- Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC
- Site US077, Fort Myers
- Site US078, Orlando
- Site US075, St. Petersburg
- and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07807163Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
- H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04429542The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
- Advent Health, Orlando
- Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
- ALX Center 7, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091DESTINY-PANTUMOUR04
- Research Site, Coral Springs
- Research Site, St. Petersburg
- Research Site, West Palm Beach
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
- Biogenix Molecular, LLC, Miami
- Advent Health Medical Group Radiation Oncology at Central Florida, Orlando
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
- University of Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222Prehabilitation Protocol for Head and Neck Cancer Patients
- University of Miami, Miami
RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 1, 2026 · NCT07318220A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
- AdventHealth Celebration, Celebration
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05076760A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
- Memorial Healthcare System, Hollywood
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
- GSK Investigational Site, St. Petersburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588PromotinG Lung Cancer screenIng Awareness and Implementation in Hispanics/Latinx Head and Neck canceR Survivors
- University of Miami, Miami
Recruiting
Ages 18 to 80 · All sexes · Updated Apr 28, 2026 · NCT06124508Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT06137274HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma
- Miami Cancer Institute, Miami
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05962242SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Jacksonville
- Massive Bio SYNERGY-AI site, Miami
- Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.