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Head and Neck Squamous Cell Carcinoma clinical trials in Arizona

18 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in Arizona.

Cities in Arizona

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Gilbert
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

  • Ironwood Cancer and Research Center, Chandler
  • University of Arizona Cancer Center, Tucson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

  • Mayo Clinic Hospital in Arizona, Phoenix
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Ironwood Cancer & Research Centers, Chandler
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

  • Cancer Center at Saint Joseph's, Phoenix
  • Banner University Medical Center - Tucson, Tucson
  • University of Arizona Cancer Center-North Campus, Tucson
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

  • Arizona Center for Cancer Care - Gilbert, Gilbert
  • Arizona Center for Cancer Care-Peoria, Peoria
  • Arizona Center for Cancer Care - Phoenix, Phoenix
  • and 3 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

  • Banner MD Anderson Cancer Center, Gilbert
  • Mayo Clinic Hospital in Arizona, Phoenix
  • Banner University Medical Center - Tucson, Tucson
  • and 1 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #67, Phoenix
  • Exelixis Clinical Site #1, Tucson
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05176483

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

  • Site #0147, Phoenix
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT06788990

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

  • Mayo Foundation for Medical Education and Research - Mayo Cl, Scottsdale
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06747585

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

  • University of Arizona Cancer Center - Tucson /ID# 262698, Tucson
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

  • Arizona Center for Cancer Care - Gilbert, Gilbert
  • Arizona Center for Cancer Care-Peoria, Peoria
  • Arizona Center for Cancer Care - Biltmore, Phoenix
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT06992427

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

  • Banner MD Anderson Cancer Center, Gilbert
  • The University of Arizona Cancer Center, Tucson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

  • HonorHealth Research Institute, Scottsdale
  • The University of Arizona Cancer Center, Tucson
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 111, Tucson
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

  • Banner MD Anderson Cancer Center, Gilbert
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

  • HonorHealth Research Institute, Scottsdale
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

  • Mayo Clinic Arizona, Phoenix
  • HonorHealth Research and Innovation Institute, Scottsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2024 · NCT06259552

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.