๐Ÿ”Ž Trials Near Me

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Headache clinical trials recruiting in the U.S.

39 studies for Headache are recruiting participants at sites across the United States.

Nearly everyone has had a headache, the most common form of pain. Learn the different types, the different symptoms of, and when to see a doctor.

By state

Recently updated studies

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache

RecruitingPhase 4
Ages 18 to 65 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06473597

EMBRACE-OBS: Single-Site Observational Registry of Patient-Reported Outcomes Following MMA Embolization for Migraine

RecruitingObservational study
Ages 18 to 64 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT07652034

Localized Injection of Lidocaine Via the Middle Meningeal Artery for Headache Treatment

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07361549

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

RecruitingObservational studyHealthy volunteers welcome
2 Months โ€“ 115 Years ยท All sexes ยท Updated Sep 22, 2026 ยท NCT00001373

Multisite Advancement of Research on Chronic Posttraumatic Headache

Recruiting
Ages 18 to 70 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT05620719

Puberty, Testosterone, and Brain Development

RecruitingObservational study
Ages 12 to 20 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06670053

Responding With Evidence and Access for Childhood Headaches

Recruiting
Ages 10 to 17 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT05889624

Tirzepatide in Idiopathic Intracranial Hypertension Trial

RecruitingPhase 4
Ages 18 to 60 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07191873

Effect of Ultrasound-Guided Dry Needling Targeting Rectus Capitus Posterior Major on Individuals With Headaches

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Sep 9, 2026 ยท NCT07309874

A Pivotal Clinical Study to Evaluate the MySalvia System for the Treatment of Resistant Migraine

Recruiting
Ages 22 to 84 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT07719608

Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual Therapy

RecruitingHealthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT07725198

Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Aug 26, 2026 ยท NCT04685772

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

RecruitingPhase 2/3
Ages 18 to 100 ยท All sexes ยท Updated Aug 18, 2026 ยท NCT06621329

Headache Ear Auditory Dizziness Sinus (HEADS) Registry

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07754266

Lidocaine Infusion Treatment for Subarachnoid Hemorrhage Headaches

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Jul 10, 2026 ยท NCT06582810

IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jul 8, 2026 ยท NCT07054801

BLOCK-SAH - PPF-Block for Post-SAH Headache

RecruitingPhase 2
Ages 18 to 85 ยท All sexes ยท Updated Jul 6, 2026 ยท NCT06008795

Chiropractic Care for Episodic Migraine

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Jun 26, 2026 ยท NCT06229834

Placebo Impacts Sleep and Pain Modulation in Chronic Pain

Recruiting
Ages 18 to 88 ยท All sexes ยท Updated Jun 17, 2026 ยท NCT06225817

An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders

Recruiting
Ages 12 and older ยท All sexes ยท Updated Jun 10, 2026 ยท NCT07639944

Determining the Utility of a Behavioral Intervention in Chronic Migraine

Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 8, 2026 ยท NCT05415020

Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage

RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated May 27, 2026 ยท NCT07116408

Bilateral Middle Meningeal Artery Lidocaine Infusion for Chronic Debilitating Migraines

RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated May 22, 2026 ยท NCT07061847

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

RecruitingObservational study
Ages 18 to 44 ยท Women ยท Updated Apr 15, 2026 ยท NCT06788977

Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Apr 13, 2026 ยท NCT07325513

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.