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Heart Failure clinical trials in Michigan
37 studies for Heart Failure are looking for participants at sites in Michigan.
Cities in Michigan
- Ann Arbor22 studies
- Detroit13 studies
- Farmington Hills9 studies
- Troy7 studies
- Grand Rapids7 studies
- Lansing3 studies
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Flint
- Research Site, Southfield
- Research Site, Southfield
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- Henry Ford Hospital, Detroit
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- AMR Dearborn, Dearborn
- Sparrow Clinical Research Institute, Lansing
- Henry Ford Providence Hospital, Southfield
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Cardiology and Vascular Associates - CAVA, Bloomfield Hills
- Henry Ford Providence Hospital, Southfield
- Michigan Heart, PC, Ypsilanti
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06935370A Study of LY3971297 in Participants With Heart Failure
- Henry Ford Health System, Detroit
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT07547540Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- University of Michigan Health System, Dominos Farms, Ann Arbor
- Embassy Research Network, Bloomfield Township
- Henry Ford Health System, Detroit
- and 3 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Farmington Hills
- Research Site, Flint
- Research Site, Troy
- and 1 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Bloomfield Hills
- Research Site, Ypsilanti
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
- University of Michigan, Ann Arbor
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 10, 2026 · NCT07098858Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- University of Michigan, Ann Arbor
- Henry Ford Health, Detriot
- Corewell Health Grand Rapids Hospital, Grand Rapids
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- University of Michigan Hospitals, Ann Arbor
- Corewell Health, Grand Rapids
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 158, Ypsilanti
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- C.S. Mott Children's Hospital ( Site 0033), Ann Arbor
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- Henry Ford, Detroit
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
- University of Michigan, Ann Arbor
RecruitingObservational study
Up to age 18 · All sexes · Updated Aug 25, 2026 · NCT06532890Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Lansing
- Ypsilanti
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
- Tenax Investigational Site, Ann Arbor
- Tenax Investigational Site, Ypsilanti
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Spectrum Health Medical Group, Grand Rapids
- Henry Ford Health System, West Bloomfield
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- Henry Ford Hospital, Detroit
Recruiting
Ages 18 to 85 · All sexes · Updated Aug 18, 2026 · NCT07214376A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- Cardio and Vascular Assoc-CAVA, Bloomfield Hills
- Corewell Health, Grand Rapids
- University Of Michigan, Lansing
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Recruiting
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT05996328Alleviant ALLAY-HF Study
- VA Ann Arbor, Ann Arbor
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303A Trial of CRD-4730 in HFrEF
- Cardurion Investigative Site, Bloomfield Hills
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Aug 6, 2026 · NCT07750873Assessment of CCM in HF With Higher Ejection Fraction
- University of Michigan, Ann Arbor
- Henry Ford St. John Hospital, Detroit
- Ascension Providence Hospital, Southfield
- and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- Henry Ford Hospital_Detroit, Detroit
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Aug 5, 2026 · NCT06979362Project 4: ACHIEVE PATHFINDER
- Henry Ford Health, Detroit
Recruiting
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06070428UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF
- Henry Ford Health, Detroit
Recruiting
Ages 18 to 89 · All sexes · Updated Jul 7, 2026 · NCT07054489A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- C.S. Mott Children's Hospital - Cardiology, Ann Arbor
RecruitingPhase 3
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Ascension Providence Hospital Cardiology - Heart Cardiology, Howell
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- C.S. Mott Children's Hospital - Cardiology, Ann Arbor
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Jun 15, 2026 · NCT07188805Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Henry Ford Hospital, Detroit
- Spectrum Health Butterworth Hospital, Grand Rapids
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
- Henry Ford Hospital, Detroit
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT06699056Cardiovascular Health Improvement Project
- University of Michigan, Ann Arbor
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 29, 2026 · NCT02306200CCM OPEN HF Registry
- University of Michigan, Ann Arbor
- Henry Ford Providence Hospital, Novi
- Trinity Ann Arbor d/b/a Michigan Heart Ann Arbor, Ypsilanti
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07112924Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
- Helen DeVos Children's Hospital, Grand Rapids
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06932081Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
- Henry Ford Health, Detroit
Recruiting
Ages 18 and older · All sexes · Updated Sep 26, 2025 · NCT06291922Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
- Henry Ford Health System, Detroit
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 18, 2025 · NCT06964464From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.