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Heart Failure clinical trials in Tennessee

32 studies for Heart Failure are looking for participants at sites in Tennessee.

Cities in Tennessee

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

  • Le Bonheur Children's Hospital ( Site 0007), Memphis
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Nov 13, 2026 · NCT05714085

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

  • Helios CR Inc, Jackson
  • East Coast Institute For Research LLC, Jefferson City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06424288

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

  • Centennial Medical Center, Nashville
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT06965504

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

  • Erlanger Health, Chattanooga
  • Stern Cardiovascular Center, Germantown
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07232030

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • The Stern Cardiovascular Foundation, Memphis
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

  • Germantown
  • Nashville
RecruitingObservational study
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

  • Stern Cardiovascular Foundation, Inc., Germantown
  • Tennova Healthcare-Turkey Creek Medical Center, Knoxville
  • Vanderbilt University Medical Center, Nashville
  • and 1 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06736574

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

  • St.Thomas Health, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07069738

ELEVATE-HFpEF Clinical Study

  • Saint Thomas Research Institute, Nashville
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Apex Research Foundation, LLC, Jackson
  • The Jackson Clinic PA, Jackson
  • Parkway Cardiology Associates, Oak Ridge
  • and 2 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Oct 29, 2026 · NCT07037459

CCM OPEN HF Registry

  • The Stern Cardiovascular Foundation, Inc, Germantown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07112924

Assessment of CCM in HF With Higher Ejection Fraction

  • The Stern Cardiovascular Foundation, Germantown
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709

Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)

  • Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 21 and older · All sexes · Updated Oct 22, 2026 · NCT07059962

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

  • Research Site, Cleveland
  • Research Site, Morristown
  • Research Site, Nashville
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

  • Research Site, Jackson
  • Research Site, Knoxville
  • Research Site, Memphis
  • and 2 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 13, 2026 · NCT06307652

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
Recruiting
Ages 60 and older · All sexes · Updated Oct 7, 2026 · NCT05996328

Alleviant ALLAY-HFrEF Study

  • Tennova Healthcare - Turkey Creek Medical Center, Knoxville
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06812533

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

  • CON-10051, Chattanooga, TN, Chattanooga
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

  • Germantown, TN Investigative Site 10063, Germantown
  • Memphis, TN Investigative Site 10059, Memphis
  • Nashville, TN Investigative Site 10071, Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM

  • Research Site, Germantown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436

Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

  • Vanderbilt University, Nashville
RecruitingObservational study
Up to age 18 · All sexes · Updated Aug 25, 2026 · NCT06532890

Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1
Ages 8 to 18 · Men · Updated Aug 24, 2026 · NCT07172971

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

  • Tristar Centennial Medical Ctr, Nashville
  • Saint Thomas Health, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  • Balad Hlth Sys-Welmont CardCVA, Greeneville
  • The Jackson Clinic, PA, Jackson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Alleviant ALLAY-HF Study

  • Stern Cardiovascular Foundation, Germantown
  • Tennova Healthcare - Turkey Creek Medical Center, Knoxville
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

  • Vanderbilt University, Nashville
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Vanderbilt, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Wearable Technology to Evaluate Hyperglycemia and HRV in DMD

  • Vanderbilt University Medical Center, Nashville
RecruitingObservational studyHealthy volunteers welcome
Ages 10 and older · Men · Updated May 22, 2026 · NCT06124196

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Centennial Medical Center, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

  • Vanderbilt University Medical Center, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06895070

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

  • University of Tennessee Medical Center, Knoxville
  • University of Tennessee Health Science Center/Regional One Health, Memphis
Recruiting
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT06374277

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.