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Heart Failure clinical trials in Tennessee
33 studies for Heart Failure are looking for participants at sites in Tennessee.
Cities in Tennessee
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- Stern Cardiovascular Foundation, Inc., Germantown
- Tennova Healthcare-Turkey Creek Medical Center, Knoxville
- Vanderbilt University Medical Center, Nashville
- and 1 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
- Erlanger Health, Chattanooga
- Stern Cardiovascular Center, Germantown
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07232030A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Helios CR Inc, Jackson
- East Coast Institute For Research LLC, Jefferson City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288Alleviant ALLAY-HFrEF Study
- Tennova Healthcare - Turkey Creek Medical Center, Knoxville
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- Apex Research Foundation, LLC, Jackson
- The Jackson Clinic PA, Jackson
- Parkway Cardiology Associates, Oak Ridge
- and 2 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Cleveland
- Research Site, Morristown
- Research Site, Nashville
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Jackson
- Research Site, Knoxville
- Research Site, Memphis
- and 2 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Germantown, TN Investigative Site 10063, Germantown
- Memphis, TN Investigative Site 10059, Memphis
- Nashville, TN Investigative Site 10071, Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- CON-10051, Chattanooga, TN, Chattanooga
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Baptist - Memphis (Stern), Memphis
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- St.Thomas Health, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- Le Bonheur Children's Hospital ( Site 0007), Memphis
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Germantown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
- Vanderbilt University, Nashville
RecruitingObservational study
Up to age 18 · All sexes · Updated Aug 25, 2026 · NCT06532890Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy
- Vanderbilt University Medical Center, Nashville
RecruitingPhase 1
Ages 8 to 18 · Men · Updated Aug 24, 2026 · NCT07172971Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Germantown
- Nashville
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
- Tenax Investigational Site, Nashville
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Tristar Centennial Medical Ctr, Nashville
- Saint Thomas Health, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- Balad Hlth Sys-Welmont CardCVA, Greeneville
- The Jackson Clinic, PA, Jackson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Stern Cardiovascular Foundation, Germantown
- Tennova Healthcare - Turkey Creek Medical Center, Knoxville
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
- Vanderbilt University, Nashville
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751Assessment of CCM in HF With Higher Ejection Fraction
- The Stern Cardiovascular Foundation, Germantown
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- Vanderbilt University Medical Center, Nashville
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Aug 5, 2026 · NCT06979362ELEVATE-HFpEF Clinical Study
- Saint Thomas Research Institute, Nashville
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Vanderbilt, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- The Stern Cardiovascular Foundation, Memphis
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Wearable Technology to Evaluate Hyperglycemia and HRV in DMD
- Vanderbilt University Medical Center, Nashville
RecruitingObservational studyHealthy volunteers welcome
Ages 10 and older · Men · Updated May 22, 2026 · NCT06124196CCM OPEN HF Registry
- The Stern Cardiovascular Foundation, Inc, Germantown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07112924The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- Centennial Medical Center, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
- Vanderbilt University Medical Center, Nashville
Recruiting
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06895070Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
- University of Tennessee Medical Center, Knoxville
- University of Tennessee Health Science Center/Regional One Health, Memphis
Recruiting
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT06374277Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim
- Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 10 and older · Men · Updated Nov 6, 2025 · NCT06093100AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
- Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 22 and older · All sexes · Updated Mar 26, 2025 · NCT06378632From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.