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High Blood Pressure clinical trials recruiting in the U.S.
183 studies for High Blood Pressure are recruiting participants at sites across the United States.
High blood pressure (hypertension) develops when blood flows through arteries at higher than normal pressures. It increases the risk for heart disease and stroke.
Cities with the most studies
- Chicago, IL21 studies
- Boston, MA21 studies
- Dallas, TX15 studies
- Nashville, TN14 studies
- Birmingham, AL12 studies
- Houston, TX11 studies
- Atlanta, GA10 studies
- Durham, NC10 studies
- Tucson, AZ10 studies
- Rochester, MN9 studies
- Philadelphia, PA9 studies
- Miami, FL9 studies
- New York City, NY9 studies
- Wichita, KS8 studies
- Orlando, FL8 studies
- Cincinnati, OH8 studies
- Arlington, VA8 studies
- Pittsburgh, PA8 studies
- Cleveland, OH8 studies
- Washington, DC8 studies
- Salt Lake City, UT7 studies
- Charlotte, NC7 studies
- Los Angeles, CA7 studies
- San Antonio, TX7 studies
- Indianapolis, IN7 studies
- Las Vegas, NV7 studies
- Jacksonville, FL7 studies
- Detroit, MI7 studies
- Richmond, VA7 studies
- Baltimore, MD7 studies
- Winston-Salem, NC6 studies
- Tampa, FL6 studies
- Mountain View, CA6 studies
- New Orleans, LA6 studies
- Charleston, SC6 studies
- San Diego, CA6 studies
- Boca Raton, FL6 studies
- Harrisburg, PA6 studies
- Austin, TX6 studies
- Aurora, CO5 studies
By state
- Alabama16 studies
- Arizona12 studies
- California29 studies
- Colorado12 studies
- Connecticut11 studies
- Florida23 studies
- Georgia20 studies
- Hawaii3 studies
- Idaho4 studies
- Illinois27 studies
- Indiana10 studies
- Iowa3 studies
- Kansas11 studies
- Kentucky5 studies
- Louisiana11 studies
- Maryland16 studies
- Massachusetts26 studies
- Michigan19 studies
- Minnesota16 studies
- Mississippi6 studies
- Missouri10 studies
- Nebraska5 studies
- Nevada9 studies
- New Jersey9 studies
- New Mexico3 studies
- New York15 studies
- North Carolina22 studies
- Ohio18 studies
- Oklahoma9 studies
- Oregon4 studies
- Pennsylvania17 studies
- South Carolina14 studies
- Tennessee20 studies
- Texas28 studies
- Utah8 studies
- Virginia12 studies
- Washington4 studies
- West Virginia3 studies
- Wisconsin3 studies
Recently updated studies
Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk
Recruiting
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07725250Home BP Monitoring
RecruitingHealthy volunteers welcome
Ages 13 to 18 · All sexes · Updated Nov 13, 2026 · NCT05552547A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Nov 12, 2026 · NCT07758634Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07181109A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Nov 12, 2026 · NCT07553442EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 70 · All sexes · Updated Nov 12, 2026 · NCT03374215A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376Gut Microbiota in Metabolic Surgery
RecruitingObservational study
Ages 21 to 65 · All sexes · Updated Nov 9, 2026 · NCT05000996Treatment of Supine Hypertension in Autonomic Failure (CPAP)
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 9, 2026 · NCT03312556The REACH-OUT Trial
Recruiting
Ages 18 to 44 · Women · Updated Nov 9, 2026 · NCT07540143A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT06742723Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot Trial
Recruiting
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07910773A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07794579A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Nov 4, 2026 · NCT07142356Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07602166A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07247162Autonomic and Renal Contributions to Hypertension With ADT
RecruitingPhase 4Healthy volunteers welcome
Ages 40 and older · Men · Updated Nov 2, 2026 · NCT07848828Dry Weight Reduction Intervention Via Extra Ultrafiltration
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07637110Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Oct 30, 2026 · NCT06402968Diabetes and Heart Disease Risk in Blacks
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Oct 29, 2026 · NCT00001853Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
Recruiting
Ages 16 to 56 · Women · Updated Oct 28, 2026 · NCT07778966Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma
RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Oct 26, 2026 · NCT03206060Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07247058From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.