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High Blood Pressure clinical trials in North Carolina

23 studies for High Blood Pressure are looking for participants at sites in North Carolina.

Cities in North Carolina

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • Cary Cardiology, Cary
  • The University of North Carolina at Chapel Hill, Chapel Hill
  • Physicians East, PA, Greenville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

  • Medication Management, Greensboro
  • Monroe Biomedical Research, Monroe
  • West Clinical Research, Morehead City
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

  • Research Site, Greenville
  • Research Site, Hickory
  • Research Site, Jacksonville
  • and 10 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06742723

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

  • NC Heart and Vascular, Raleigh
Recruiting
Ages 22 to 75 · All sexes · Updated Sep 24, 2026 · NCT06559891

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

  • HCA Asheville Cardiology Associates, Asheville
  • Atrium Health - Sanger Heart, Charlotte
  • WakeMed, Raleigh
Recruiting
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06059638

Lifestyle Intervention In CKD

  • Sarah W Stedman Nutrition & Metabolism Center, Durham
Recruiting
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07633145

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Durham
  • Clinical Trial Site, Greenville
  • Clinical Trial Site, High Point
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

  • Retension Clinical Site, Asheboro
  • Retension Clinical Site, Charlotte
  • Retension Clinical Site, Monroe
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT07142356

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

  • Duke University Health System, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

Global Paradise System US Post Approval Study

  • University of North Carolina at Chapel Hill School of Medicine, Chapel Hill
  • Durham VA Health System, Durham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

  • Monroe Biomedical Research, Monroe
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07543120

A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia

  • Monroe Biomedical Research, Monroe
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jul 30, 2026 · NCT07610278

SPYRAL GEMINI Pilot Study

  • University of North Carolina (UNC) Memorial Hospital, Chapel Hill
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 24, 2026 · NCT06907147

'Eat Well' Produce Prescription RCT

  • Durham VA Health Care System, Durham
Recruiting
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT07534501

Remote Hypertension Management for Black Patients

  • Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 21 to 85 · All sexes · Updated Jun 2, 2026 · NCT06527794

Low Energy Availability and Hypertension in Division I HBCU Athletes

  • North Carolina Agricultural & Technical State University, Greensboro
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 26 · All sexes · Updated May 13, 2026 · NCT07583940

Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity

  • Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07031739

Telehealth and Remote Blood Pressure

  • Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 18 to 45 · Women · Updated Apr 27, 2026 · NCT07356518

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

  • Vanda Investigative Site, Kinston
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Feb 27, 2026 · NCT07090161

Improving Hypertension Control in Rheumatoid Arthritis

  • Duke Health System, Durham
Recruiting
Ages 18 and older · All sexes · Updated Feb 6, 2026 · NCT05760898

RCT of Sensor-controlled Digital Game for Hypertension Self-care in a Native American Community

  • University of North Carolina Chapel Hill, Chapel Hill
Recruiting
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT05671406

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)

  • Wake Forest Health Sciences, Winston-Salem
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 18 · All sexes · Updated Dec 11, 2025 · NCT04752293

Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US

  • Duke University - Charlotte Study Sites, Charlotte
  • Duke University - Duke Study Site, Durham
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 24, 2025 · NCT05129345

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.