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Hypothyroidism clinical trials recruiting in the U.S.
9 studies for Hypothyroidism are recruiting participants at sites across the United States.
Hypothyroidism happens when your thyroid gland does not make enough thyroid hormone to meet your body's needs. Hypothyroidism is more common in women.
By state
Recently updated studies
Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
RecruitingObservational study
1 Month – 80 Years · All sexes · Updated Sep 22, 2026 · NCT02089789Natural History of Thyroid Function Disorders
RecruitingObservational study
6 Months – 98 Years · All sexes · Updated Sep 16, 2026 · NCT00001159Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
Recruiting
Ages 65 and older · All sexes · Updated Sep 4, 2026 · NCT06629272An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets.
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 5, 2026 · NCT07747103Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)
RecruitingObservational study
All ages · All sexes · Updated Aug 4, 2026 · NCT06669949Novel Approaches to the Treatment of Hypothyroidism
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Mar 19, 2026 · NCT06731764Dosing of LT4 in Older Individuals
RecruitingPhase 4
Ages 65 and older · All sexes · Updated Feb 19, 2026 · NCT06073665A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
RecruitingPhase 2/3
Ages 18 to 75 · All sexes · Updated Jan 5, 2026 · NCT06345339A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
Recruiting
Ages 18 to 75 · All sexes · Updated Sep 8, 2025 · NCT03977207From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.