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Hypothyroidism clinical trials recruiting in the U.S.

9 studies for Hypothyroidism are recruiting participants at sites across the United States.

Hypothyroidism happens when your thyroid gland does not make enough thyroid hormone to meet your body's needs. Hypothyroidism is more common in women.

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Recently updated studies

Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation

RecruitingObservational study
1 Month – 80 Years · All sexes · Updated Sep 22, 2026 · NCT02089789

Natural History of Thyroid Function Disorders

RecruitingObservational study
6 Months – 98 Years · All sexes · Updated Sep 16, 2026 · NCT00001159

Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

Recruiting
Ages 65 and older · All sexes · Updated Sep 4, 2026 · NCT06629272

An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets.

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 5, 2026 · NCT07747103

Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

RecruitingObservational study
All ages · All sexes · Updated Aug 4, 2026 · NCT06669949

Novel Approaches to the Treatment of Hypothyroidism

RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Mar 19, 2026 · NCT06731764

Dosing of LT4 in Older Individuals

RecruitingPhase 4
Ages 65 and older · All sexes · Updated Feb 19, 2026 · NCT06073665

A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients

Recruiting
Ages 18 to 75 · All sexes · Updated Sep 8, 2025 · NCT03977207

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.