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Immune System and Disorders clinical trials recruiting in the U.S.
43 studies for Immune System and Disorders are recruiting participants at sites across the United States.
Your immune system is made up of cells, tissues, and organs that fight infections and diseases. Learn how it works, and about diseases of the immune system.
Cities with the most studies
- Washington, DC13 studies
- New York City, NY12 studies
- Philadelphia, PA10 studies
- Boston, MA10 studies
- Atlanta, GA9 studies
- Houston, TX9 studies
- Portland, OR9 studies
- Cleveland, OH8 studies
- Los Angeles, CA8 studies
- Chicago, IL8 studies
- Milwaukee, WI6 studies
- Cedar Rapids, IA6 studies
- Seattle, WA6 studies
- Durham, NC5 studies
- Tampa, FL5 studies
- Nashville, TN5 studies
- Baldwin Park, CA5 studies
- Salt Lake City, UT5 studies
- St. Louis, MO4 studies
- Dallas, TX4 studies
- Pittsburgh, PA4 studies
- Clifton, NJ4 studies
- Greenville, NC3 studies
- Kansas City, MO3 studies
- Norfolk, VA3 studies
- Louisville, KY3 studies
- San Diego, CA3 studies
- The Bronx, NY3 studies
- Indianapolis, IN3 studies
- New Haven, CT3 studies
- Denver, CO3 studies
- Orlando, FL3 studies
- Columbus, OH3 studies
- Rochester, MN3 studies
- San Francisco, CA3 studies
- Phoenix, AZ3 studies
- Mountain View, CA3 studies
- Omaha, NE3 studies
- Richmond, VA3 studies
- Cincinnati, OH3 studies
By state
- Arizona3 studies
- Arkansas3 studies
- California18 studies
- Colorado4 studies
- Connecticut3 studies
- District of Columbia3 studies
- Florida11 studies
- Georgia10 studies
- Illinois9 studies
- Indiana4 studies
- Iowa6 studies
- Kentucky4 studies
- Maryland13 studies
- Massachusetts10 studies
- Michigan4 studies
- Minnesota4 studies
- Missouri6 studies
- Nebraska3 studies
- New Jersey6 studies
- New York14 studies
- North Carolina7 studies
- Ohio9 studies
- Oregon9 studies
- Pennsylvania12 studies
- South Carolina3 studies
- Tennessee5 studies
- Texas14 studies
- Utah5 studies
- Virginia6 studies
- Washington7 studies
- Wisconsin6 studies
Recently updated studies
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
RecruitingPhase 2Healthy volunteers welcome
Ages 4 to 75 · All sexes · Updated Sep 28, 2026 · NCT02579967Detection and Characterization of Infections and Infection Susceptibility
RecruitingObservational study
1 Month – 100 Years · All sexes · Updated Sep 28, 2026 · NCT00404560Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia
RecruitingObservational study
Ages 1 to 100 · All sexes · Updated Sep 28, 2026 · NCT00001406Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 100 · All sexes · Updated Sep 28, 2026 · NCT01568697Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
RecruitingObservational studyHealthy volunteers welcome
1 Month – 120 Years · All sexes · Updated Sep 28, 2026 · NCT00006150Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity
RecruitingPhase 2
Ages 4 to 69 · All sexes · Updated Sep 28, 2026 · NCT04339777Genetic Analysis of Immune Disorders
RecruitingObservational study
1 Day – 101 Years · All sexes · Updated Sep 25, 2026 · NCT00001467A Study of JADE101 in Participants With Immunoglobulin A Nephropathy
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Sep 25, 2026 · NCT07541287Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System
RecruitingObservational studyHealthy volunteers welcome
1 Month – 99 Years · All sexes · Updated Sep 22, 2026 · NCT00794352A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06722235Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects
RecruitingObservational study
All ages · All sexes · Updated Sep 17, 2026 · NCT04242095(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)
RecruitingPhase 2
Ages 18 to 69 · All sexes · Updated Sep 15, 2026 · NCT07699380A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06948318PS-002 for the Treatment of IgA Nephropathy in Adults
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07182227A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to-Severe Eczema
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 4, 2026 · NCT07765888A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07075185Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT05826535A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07192471A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
RecruitingPhase 1/2
Ages 35 to 70 · All sexes · Updated Aug 21, 2026 · NCT06575426Abatacept for the Treatment of Giant Cell Arteritis
RecruitingPhase 3
Ages 50 and older · All sexes · Updated Aug 20, 2026 · NCT04474847A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study
Recruiting
Ages 18 to 80 · All sexes · Updated Aug 17, 2026 · NCT07759115Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Aug 17, 2026 · NCT06858319A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
RecruitingPhase 2
Ages 18 to 74 · All sexes · Updated Aug 12, 2026 · NCT07037901From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.