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Inflammatory Bowel Disease clinical trials recruiting in the U.S.

73 studies for Inflammatory Bowel Disease are recruiting participants at sites across the United States.

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Recently updated studies

A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07845487

Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease

RecruitingObservational study
Ages 18 to 85 · All sexes · Updated Sep 29, 2026 · NCT07619547

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07012395

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT06619990

Immune Regulation in Ulcerative Colitis or Crohn s Disease

RecruitingObservational studyHealthy volunteers welcome
1 Day – 75 Years · All sexes · Updated Sep 28, 2026 · NCT00001184

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Sep 25, 2026 · NCT05923073

Non-nutritive Sweeteners in Inflammatory Bowel Disease

RecruitingHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 25, 2026 · NCT07769437

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

Study of DISC-0974-201 in Participants With IBD and Anemia

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07368972

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 22, 2026 · NCT06226883

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Sep 22, 2026 · NCT04685200

Observational Pharmaco-Epidemiology Research & Analysis

RecruitingObservational studyHealthy volunteers welcome
Ages 0 and older · All sexes · Updated Sep 11, 2026 · NCT03813862

Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome

RecruitingObservational study
1 Month – 115 Years · All sexes · Updated Sep 9, 2026 · NCT00001456

Familial Inflammatory Bowel Disease Early Risk

RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 55 · All sexes · Updated Aug 28, 2026 · NCT07791862

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Aug 24, 2026 · NCT05509777

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06274554

A Multicenter National Prospective Study of Pregnancy and Neonatal Outcomes in Women With Inflammatory Bowel Disease

RecruitingObservational study
Ages 18 to 45 · Women · Updated Aug 11, 2026 · NCT00904878

HB-adMSCs for the Treatment of Crohn's Disease

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Aug 6, 2026 · NCT07077746

BOOM-IBD2 Pivotal Clinical Trial

Recruiting
Ages 18 to 85 · All sexes · Updated Aug 6, 2026 · NCT06571669

Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06266663

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

Impact of the Enhanced Recovery After Surgery System for Colorectal Surgery

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT02997293

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.