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Kidney Cancer clinical trials recruiting in the U.S.

58 studies for Kidney Cancer are recruiting participants at sites across the United States.

Kidney cancer symptoms are hard to detect at first but they do exist. Read more about the top 5 symptoms and the treatment options available

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Recently updated studies

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT05536141

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Nov 12, 2026 · NCT00033137

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Nov 10, 2026 · NCT00050752

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Nov 9, 2026 · NCT00026884

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Nov 5, 2026 · NCT03160274

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 4, 2026 · NCT05366881

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Nov 4, 2026 · NCT00001238

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07300241

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07011719

A Study of a Side Effects and Resource Navigation Program for People With Cancer

Recruiting
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07646847

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT04981119

A Study of Treatment Delivery Preference In People With Kidney Cancer

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07872553

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

RecruitingObservational studyHealthy volunteers welcome
4 Weeks · All sexes · Updated Oct 16, 2026 · NCT01109394

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06026410

A Study of HC-7366 in Combination With Belzutifan (WELIREGâ„¢) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05287945

A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07401875

A Study of Theranostic Pair PD-32766D/T in Participants With Carbonic Anhydrase IX Positive Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07688187

Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT06948552

Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALA

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07828704

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.