A Study of a Side Effects and Resource Navigation Program for People With Cancer

Recruiting

I CARE (Immunotherapy Cutaneous Adverse Events REsearch) - A Trial With Diverse Cancer Patients to Determine the Impact of SDoH and Side Effects Navigation Program on Treatment Continuation

Who can join

Ages 18 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

* Documentation of Disease

  o Patient must have pathologically confirmed kidney, bladder, breast, or lung cancer (per EMR)
* Prior Treatment

  o Within three weeks (+/- 3 weeks) of starting PD-1 or PD(L)-1 immune checkpoint inhibitors as monotherapy or in combination with other therapies (per EMR)
* Age ≥ 18 (per EMR)
* Not Pregnant and Not Nursing (per self-report)
* At least one essential need (e.g., food, transportation, housing), as determined by the ICCAN Essential Needs Screener (per self-report)
* Lives in New York metro area, including Long Island, New Jersey, Connecticut, and Pennsylvania (per self-report)
* Can speak English or Spanish (per self-report)
* Has no significant psychiatric disturbance sufficient to preclude completion of the assessment measures, interview, or informed consent (i.e., acute psychiatric symptoms which require individual treatment) (per EMR, patient's care team, or study team)
* Has no presence of cognitive impairment disorder (i.e., delirium or dementia) sufficient to preclude meaningful informed consent and/or data collection (per EMR, patient's care team, or study team)

About the study

The purpose of this study is to find out if the navigation program helps participants manage immunotherapy treatment better than usual care. Investigators will also look at how the navigation program impacts participants' quality of life. Investigators will measure quality of life by having participants complete questionnaires.

What is being tested

Immunotherapy CARE Program (other)

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 200 · Started: Sep 14, 2026

Contact the study team

Francesca Gany, MD, MS · Phone: 646-888-8054
Neil Shah, MBBS · Phone: 646-888-4239

Official record on ClinicalTrials.gov — NCT07646847

Locations in the U.S.

New Jersey	Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale
New York	Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities), Commack Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison City College of New York (Data Collection AND Specimen Analysis), New York (Not yet recruiting) Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York Memorial Sloan Kettering Nassau (All protocol activities), Rockville Centre

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.