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Liver Diseases clinical trials recruiting in the U.S.
33 studies for Liver Diseases are recruiting participants at sites across the United States.
Get the facts about liver diseases, such as hepatitis, cancer, and cirrhosis. Know your risk and what you can do to prevent liver problems.
Cities with the most studies
- Chicago, IL10 studies
- Houston, TX10 studies
- Los Angeles, CA8 studies
- Washington, DC8 studies
- Atlanta, GA8 studies
- New York City, NY7 studies
- San Antonio, TX6 studies
- Philadelphia, PA6 studies
- Richmond, VA6 studies
- Durham, NC5 studies
- Ann Arbor, MI5 studies
- Aurora, CO5 studies
- Dallas, TX5 studies
- Cleveland, OH4 studies
- Miami, FL4 studies
- St. Louis, MO4 studies
- Cincinnati, OH4 studies
- Detroit, MI4 studies
- Pittsburgh, PA4 studies
- Nashville, TN4 studies
- Austin, TX4 studies
- Orlando, FL4 studies
- San Diego, CA4 studies
- Little Rock, AR4 studies
- Chandler, AZ4 studies
- Baltimore, MD4 studies
- Salt Lake City, UT4 studies
- Dayton, OH3 studies
- Hialeah, FL3 studies
- Columbia, SC3 studies
- Fort Worth, TX3 studies
- Monroe, LA3 studies
- Round Rock, TX3 studies
- Carrollton, TX3 studies
- Jacksonville, FL3 studies
- Fayetteville, NC3 studies
- Seattle, WA3 studies
- Ocala, FL3 studies
- Charlotte, NC3 studies
- Las Vegas, NV3 studies
By state
- Arizona5 studies
- Arkansas4 studies
- California13 studies
- Colorado7 studies
- Florida8 studies
- Georgia9 studies
- Illinois10 studies
- Indiana6 studies
- Kansas3 studies
- Kentucky3 studies
- Louisiana3 studies
- Maryland9 studies
- Massachusetts5 studies
- Michigan8 studies
- Minnesota3 studies
- Missouri5 studies
- Nevada3 studies
- New Jersey3 studies
- New York8 studies
- North Carolina6 studies
- Ohio7 studies
- Oregon3 studies
- Pennsylvania8 studies
- South Carolina3 studies
- Tennessee4 studies
- Texas14 studies
- Utah6 studies
- Virginia6 studies
- Washington3 studies
Recently updated studies
Evaluation of Patients With Liver Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 100 · All sexes · Updated Sep 24, 2026 · NCT00001971Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT07654283Natural History of Noncirrhotic Portal Hypertension
RecruitingObservational study
Ages 12 to 100 · All sexes · Updated Sep 22, 2026 · NCT02417740Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Sep 22, 2026 · NCT04685200Study of Resmetirom in Children and Adolescents With MASH
RecruitingPhase 2
Ages 6 to 17 · All sexes · Updated Sep 11, 2026 · NCT07763015Observational Pharmaco-Epidemiology Research & Analysis
RecruitingObservational studyHealthy volunteers welcome
Ages 0 and older · All sexes · Updated Sep 11, 2026 · NCT03813862A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 9, 2026 · NCT07288138A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 3, 2026 · NCT06419374A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 3, 2026 · NCT06318169Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)
RecruitingObservational study
7 Months – 15 Months · All sexes · Updated Aug 31, 2026 · NCT06805695An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency
RecruitingPhase 3
24 Hours – 7 Months · Men · Updated Aug 12, 2026 · NCT06255782Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07010315Primary Sclerosing Cholangitis in Children
RecruitingObservational study
Ages 2 to 25 · All sexes · Updated Jul 14, 2026 · NCT04181138Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 25, 2026 · NCT06068491Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
Recruiting
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06138821A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment
RecruitingPhase 1
Ages 18 to 80 · All sexes · Updated Jun 16, 2026 · NCT07559474Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT03193151Metabolic Responses to Bariatric Surgery
RecruitingObservational study
Ages 18 to 55 · All sexes · Updated May 18, 2026 · NCT02024542Microbiome Modulation With Prebiotics in PTSD and Cirrhosis
Recruiting
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06464952DILIN - Prospective Study
RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Apr 8, 2026 · NCT00345930Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients
Recruiting
Ages 18 and older · All sexes · Updated Feb 3, 2026 · NCT06269510MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 14, 2026 · NCT05264051A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Dec 15, 2025 · NCT06619561The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT06871111From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.