Observational Pharmaco-Epidemiology Research & Analysis
OPERA Longitudinal Observational Database in the Study of Chronic Diseases, Treatments and Outcomes
Who can join
Ages 0 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Patients who are treated in the practices who enroll and participate in the study * Patients whose treatment is documented in the practice's electronic health record system Exclusion Criteria: * Patients who opt out of OPERA
About the study
Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management; and 2) the use of the point-of-care observational data from the provider-patient encounter that support realworld medical research and healthcare quality measure assessment. Real-world evaluations of treatments of chronic diseases in the context of comorbid conditions and special populations (minorities, women, mentally ill, and those with addiction) are limited. The purpose of the OPERA database is to help address this unmet need in clinical research.
What is being tested
- Non-interventional (observational only) (other)
Sponsor: Epividian · Participants: 2,000,000 · Started: Dec 1, 2013
Contact the study team
- Gregory Fusco, MD · Phone: 224-632-1862
Official record on ClinicalTrials.gov — NCT03813862
Locations in the U.S.
| North Carolina | Epividian, Durham |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.